Results 301 to 310 of about 20,208,357 (389)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Retraction Note: Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression. [PDF]

Nat Commun
Weng ML, Chen WK, Chen XY, Lu H, Sun ZR, Yu Q, Sun PF, Xu YJ, Zhu MM, Jiang N, Zhang J, Zhang JP, Song YL, Ma D, Zhang XP, Miao CH.   +15 more
europepmc   +1 more source

Chart II. Tracks of Centers of Anticyclones, May 1940. (Inset) Departure of Monthly Mean Pressure from Normal

, 1940

openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Correction: Transcriptomic analysis of differential expression between surviving and nonsurviving patients infected by the SARS-CoV-2 Delta variant. [PDF]

Sci Rep
Vlasov I, Usenko T, Panteleeva A, Nikolaev M, Izumchenko A, Panafidina V, Gavrilova E, Shlyk I, Miroshnikova V, Polushin Y, Shadrina M, Pchelina S, Slominsky P.   +12 more
europepmc   +1 more source

Chart III. Tracks of Centers of Cyclones, January 1940. (Inset) Change in Mean Pressure from Preceding Month

, 1940

openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Evaluating Patient Experience With Genomic Medicine: A Content Analysis of National Cancer Institute-Designated Cancer Centers' Websites.

JMIR Cancer
Andriessen AS, Saulsberry L.
europepmc   +1 more source

Correction: Clinical Outcomes of Eravacycline in Patients Treated for Stenotrophomonas maltophilia Infections. [PDF]

Infect Dis Ther
Al Musawa M, Kunz Coyne AJ, Alosaimy S, Lucas K, Schrack MR, Andrade J, Herbin SR, Biagi M, Pierce M, Molina KC, DeKerlegand A, Perkins NB, Cosimi R, Kang-Birken L, King MA, Pullinger BM, Rojas LM, Bouchard J, Hobbs ALV, Agee J, Caniff KE, Van Helden SR, Veve MP, Rybak MJ.   +23 more
europepmc   +1 more source