Results 231 to 240 of about 2,076,711 (304)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Protocol for profiling chromatin accessibility in human small-cell lung cancer FFPE-derived samples using Omni-ATAC-seq. [PDF]

STAR Protoc
Salataj E, Kawasaki K, Massagué J, Rudin CM, Whitehouse I, Koche R, Hamard PJ.   +6 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Functional reorganization of motor subcircuits in Parkinson's disease. [PDF]

Brain Commun
Theofanopoulou C, Bajaj N, Muñoz Sánchez A, Crosson B, Wolf SL, Krishnamurthy V, McGregor KM, Hackney ME.   +7 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Detecting drug-induced nephrotoxicity using simultaneous label-free autofluorescence multiharmonic microscopy. [PDF]

Toxicol Sci
Alex A, Shi J, Chaney EJ, Doan M, Fisher CP, Obert L, Ishiy C, Ho A, Spillman DR, Marjanovic M, Roger J, Groseclose MR, Hood SR, Boppart SA.   +13 more
europepmc   +1 more source

[Regional Center of Perinatology].

Ginekologia polska, 1985
openaire   +1 more source

Prioritizing Emergency Medical Conditions for Health Policy Using a Stepwise Treatable-Death Framework: A Nationwide Analysis in Korea, 2018-2022. [PDF]

J Clin Med
Jeongmin M, Yoon C, Hyun JH, Park SH, Kim K.   +4 more
europepmc   +1 more source

Disentangling polymer confinement from specific-folding interactions reveals the drivers of Escherichia coli chromosome organization. [PDF]

Nucleic Acids Res
Delafrouz P, Nesterova T, Harris FE, Farooq H, Du L, Liu J, Ma A, Xiao J, Liang J.   +8 more
europepmc   +1 more source