Results 31 to 40 of about 128,081 (229)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Luhmann, Lotman and the problem of boundary: a critical reflexion of the theoretical categories of inclusion and exclusion

open access: yesRevista de Ciências Humanas, 2016
This paper intends to give insight to the recent debate in Germany about inclusion and exclusion and the existing difficulties in the scientific discussion with both categories, especially concerning a theoretical definition.
Jan Steffens, Suene de Souza Dantas
doaj   +1 more source

An (Un)Marked Foreigner: Race-Making in Egyptian, Syrian, and German Popular Cultures

open access: yesLateral, 2021
This essay negotiates the critical tension between race as an analytic and social construct by examining how race becomes socialized in and through the production and presentation of Arab culture in two ethnographic case studies: how Syrian musicians ...
Shayna Silverstein, Darci Sprengel
doaj   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Syntax-Semantics Interaction in Mathematics

open access: yesStudia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxii2.06 MICHAEL HELLER SYNTAX–SEMANTICS INTERACTION IN MATHEMATICS SU M M A R Y: Mathematical tools of category theory are employed to study the syntax-semantics problem in the philosophy of mathematics.
Michael Heller
doaj  

The representation theorem of the Robinson hybrid

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
This research lies within the domain of model theory, which investigates the properties of, broadly speaking, incomplete theories. The article introduces novel methods for classifying classes of structures whose associated theories are Jonssonian ...
N.M. Mussina, O.I. Ulbrikht
doaj   +1 more source

Patients' experiences of the complex trust-building process within digital cardiac rehabilitation.

open access: yesPLoS ONE, 2021
The development of digital solutions is becoming increasingly important in facing global challenges. Therefore, research on this topic is important in taking into account cardiac patients' experiences of the rehabilitation process for the design of ...
Marjo-Riitta Anttila   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Professional responsibility-acquiring process among bachelor degree nursing students: A grounded theory study

open access: yesJournal of Education and Health Promotion, 2020
INTRODUCTION:Professional responsibility-acquiring process among bachelor degree nursing students is important for their current and future performance and educational and health-care system, but this process has not been explored in the literature.
Saeed Ghasemi   +2 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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