Results 61 to 70 of about 10,758,453 (263)

The Academic Medical Center Linear Disability Score (ALDS) item bank: item response theory analysis in a mixed patient population

open access: yesHealth and Quality of Life Outcomes, 2005
Background Currently, there is a lot of interest in the flexible framework offered by item banks for measuring patient relevant outcomes. However, there are few item banks, which have been developed to quantify functional status, as expressed by the ...
Vermeulen Marinus   +6 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

'You're not just a medical professional': Exploring paramedic experiences of overdose response within Vancouver's downtown eastside.

open access: yesPLoS ONE, 2020
BackgroundOverdose response has become an increasingly relevant component of paramedic practice, particularly in light of increased opioid overdose globally.
Jordan Williams-Yuen   +4 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Development of the performance prediction algorithms for cloud services

open access: yesSistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2018
Main stages of data center service performance prediction were discussed, specifically data monitoring and gathering, calculation and prediction of key indexes and performance index prediction.
Denis O. Zuev   +3 more
doaj   +1 more source

Contributions to inflation after euro adoption: the case of Central and Eastern European countries

open access: yesEkonomia i Prawo, 2020
Motivation: Based on theory, the introduction of a single currency should cause a decrease in transaction costs, which in effect should lead to a drop in consumer prices.
Kamil Kotliński
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Experiencing the education process in physical rehabilitation

open access: yesRevista da Escola de Enfermagem da USP
Objective: To interpret and build a theoretical model of the user’s experience in the education process in physical rehabilitation settings. Method: Qualitative research, based on the Grounded Theory. The setting was a Rehabilitation Center of Rede Lucy
Simone Nunes Pereira   +3 more
doaj   +2 more sources

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