Results 81 to 90 of about 176,712,561 (267)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
100 Glimpses : Sight Center Summer Camp Program
100 Glimpses is a series of short documentaries produced by the Sight Center of Northwest Ohio. The series explores the organization's history. The Sight Center was founded in 1923 as the Toledo Society for the Blind.
Sight Center of Northwest Ohio (Toledo, Ohio)
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
100 Glimpses : Sister Linda Meets The Sight Center
100 Glimpses is a series of short documentaries produced by the Sight Center of Northwest Ohio. The series explores the organization's history. The Sight Center was founded in 1923 as the Toledo Society for the Blind.
Sight Center of Northwest Ohio (Toledo, Ohio)
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
100 Glimpses : Prevention of Blindness
100 Glimpses is a series of short documentaries produced by the Sight Center of Northwest Ohio. The series explores the organization's history. The Sight Center was founded in 1923 as the Toledo Society for the Blind.
Sight Center of Northwest Ohio (Toledo, Ohio)
core
100 Glimpses : Dr. Harry S. Will
, 2023 100 Glimpses is a series of short documentaries produced by the Sight Center of Northwest Ohio. The series explores the organization's history. The Sight Center was founded in 1923 as the Toledo Society for the Blind.
Sight Center of Northwest Ohio (Toledo, Ohio)
core