Results 171 to 180 of about 1,354,013 (264)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Open Versus Closed Kinetic Chain: Exercise Effects on Center of Pressure and Y-Balance in Middle-Aged Women with Knee Osteoarthritis-A Randomized Controlled Trial. [PDF]

Healthcare (Basel)
Kang J, Lee JY, Park IB.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Impact of Aging and Visual Input on Postural Stability in Dogs: Insights from Center-of-Pressure Analysis. [PDF]

Sensors (Basel)
Lutonsky C, Peham C, Affenzeller N, Aghapour M, Wegscheider J, Tichy A, Bockstahler B.   +6 more
europepmc   +1 more source

The Center of Pressure in Peripheral Diabetic Neuropathy

Open access Journal of Neurology & Neurosurgery, 2017
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Estimation of 3D Ground Reaction Force and 2D Center of Pressure Using Deep Learning and Load Cells Across Various Gait Conditions. [PDF]

Sensors (Basel)
Kim J, Kim KC, Tack G, Choi JS.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Correction: Center of Pressure of Medial Knee Contact Force Predicts Future Transition Risk of Knee Surgery in Patients with Knee Osteoarthritis. [PDF]

Ann Biomed Eng
Yamagata M, Taniguchi M, Tateuchi H, Motomura Y, Kobayashi M, Ichihashi N.   +5 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source