Results 41 to 50 of about 19,097 (313)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
The Effect of the Pivot Stiffness on the Performances of Five-Pad Tilting Pad Bearings
Lubricants, 2019 The role of the pivot flexibility in tilting-pad journal bearings (TPJBs) has become essential, particularly for bearings working at high applied load and relatively high rotor speeds.
Phuoc Vinh Dang +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Smart Agricultural Technology, 2022 It is essential to know the dynamics of agricultural areas through surface energy balance components such as radiation balance, evapotranspiration, and soil moisture for the sustainable management of water use in irrigation.
Jhon Lennon Bezerra da Silva +7 more
doaj +1 more source
Precision Irrigation Guide for Center Pivots
, 2022 This factsheet discusses the different variable rate irrigation (VRI) options for center pivots, when they might reduce water use and energy, produce higher crop yields, and when it might be unreasonable to expect these kinds of benefits.
Flint, Elisa +5 more
openaire +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Suitability of Reduced Pressure Center‐Pivots
Journal of Irrigation and Drainage Engineering, 1984 Selection criteria for reduced pressure center‐pivot irrigation systems are developed. An analysis of the combined effects of the application rate characteristics or center‐pivot irrigation systems and the Soil Conservation Service (SCS) soil intake family curves is used to determine the maximum depth of water which could be applied per irrigation for ...
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Scientia Agricola, 1994 Com o objetivo de desenvolver um modelo de programação linear para simular os níveis das atividades do processo de produção, utilizou-se o sistema de produção da fazenda Lagoa do Fogão, propriedade da família Sakai, localizada no município de Guaíra,SP ...
J.A. Frizzone +3 more
doaj +1 more source