Results 131 to 140 of about 17,919,985 (298)

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

KEJADIAN CENTRAL LINE ASSOCIATED BLOODSTREAM INFECTION DI RUANG RAWAT INTENSIF RSUD DR ZAINOEL ABIDIN BANDA ACEH [PDF]

, 2016
Infeksi nososkomial merupakan salah satu indikator untuk melihat kualitas pelayanan kesehatan di rumah sakit. Salah satu infeksi nosokomial di Ruang Rawat Intensif yang sering terjadi dan memperpanjang masa rawatan adalah Central Line Associated ...
Khairunnisa
core  

Antimicrobial locks for the prevention of central line associated bloodstream infections in pediatric patients: a systematic review and network meta-analysis

Antimicrobial Resistance and Infection Control
Background Central-line-associated bloodstream infections (CLABSI) impart substantial morbidity and mortality worldwide Neonates and other pediatric patients with chronic conditions that require long-term central access are at the highest risk and often ...
Nathan L’Etoile, Yun Li, Ericka Hayes, Susan E. Coffin   +3 more
doaj   +1 more source

Shared Genetic Pathways Linking Oral Diseases to Gastrointestinal Disorders: An Integrative Multi‐Omics Study

iMetaMed, EarlyView.
Shared genetics pathways connect oral diseases and gut disorders. ABSTRACT Oral diseases are highly prevalent and increasingly recognized as contributors to gastrointestinal disorders. Despite clinical observations of oral–gut comorbidity, the underlying genetic architecture and causal mechanisms remain poorly understood.
Rui Zhang, Yuelan Gao, Yuyang Zhao, Wanyang Zhong, Xingxiang Duan, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection

iMeta, EarlyView.
This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu, Xiuying Tao, Dan Fang, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +5 more
wiley   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye, M. B. Komane, A. P. Manyisane, R. Manganyi   +3 more
wiley   +1 more source

The impact of private equity acquisition of US hospitals on patient outcomes: A systematic review

Journal of Hospital Medicine, EarlyView.
Abstract Background Private equity (PE) firms are increasingly acquiring US hospitals. While PE ownership may infuse capital and managerial expertise, restructuring by organizations with limited patient‐care experience raises safety concerns. The effect of PE ownership on hospital outcomes remains poorly defined.
Angad S. Sidhu, Nikola S. Vuckovic, Salil Gupta, Christopher M. Garcia, Manav B. Patel, Cristiane M. Ueno   +5 more
wiley   +1 more source

Biofilm-associated candidal thrombophlebitis

IDCases, 2023
Shinnosuke Fukushima, Koichiro Yamamoto, Yasuhiro Nakano, Hideharu Hagiya, Fumio Otsuka   +4 more
doaj   +1 more source