Alimentary Pharmacology &Therapeutics, EarlyView.In this nationwide study of patients with inflammatory bowel disease, TNF inhibitor use was associated with higher bloodstream infection rates, whereas vedolizumab and ustekinumab was not. Associations differed by pathogen species, and concomitant glucocorticoid use was associated with higher infection rates.
Cæcilie Leding +4 more
wiley +1 more source
Implementation of central venous access device care bundles using a plan-do-study-act approach to reduce central line-associated bloodstream infection in children at a tertiary hospital in Indonesia. [PDF]
Front PediatrPrawira Y +6 more
europepmc +1 more source
Controlling the chaos: Information management in home-infusion central-line-associated bloodstream infection (CLABSI) surveillance. [PDF]
Antimicrob Steward Healthc Epidemiol, 2023 Hannum SM +9 more
europepmc +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source
The Role of Artificial Intelligence in Managing Central Line-Associated Bloodstream Infection (CLABSI) for Patient Safety and Quality of Care. [PDF]
Risk Manag Healthc PolicySaad AA +5 more
europepmc +1 more source
Characteristics, costs, and outcomes associated with central-line-associated bloodstream infection and hospital-onset bacteremia and fungemia in US hospitals. [PDF]
Infect Control Hosp Epidemiol, 2023 Yu KC, Jung M, Ai C.
europepmc +1 more source
CD93—An emerging vascular target in cancer therapy
British Journal of Pharmacology, EarlyView.Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira +3 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral +3 more
wiley +1 more source
Early detection of central line-associated bloodstream infection in intensive care unit patients using the systemic inflammatory response index (SIRI). [PDF]
GMS Hyg Infect ControlLahariya R, Anand G.
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Cell Proliferation, EarlyView.DPSC‐IVs suppressed PI3K/AKT/mTOR signalling pathway by delivering PTEN to tumour cells, which reduced the expression of Bcl‐2 and elevated that of Bax. Meanwhile, DPSC‐IVs activated PINK1/Parkin mediated mitophagy, which further raised ROS levels.
Yu Luo +10 more
wiley +1 more source