Results 231 to 240 of about 1,789,263 (297)

Exploring the nexus between hydroclimatic variability, population growth, land use land cover change, and long-term upper Nyong Basin River chemistry (Central Africa rainforest). [PDF]

Sci Rep
Komba DE, Nkoue Ndondo GR, Riotte J, Audry S, Nlend B, Nka Nnomo B, Ngo Boum-Nkot S, Ateba Bessa H, Fongoh EJ, Boithias L, Lagane C, Ndam Ngoupayou JR, Ntamak-Nida MJ, Etame J, Braun JJ.   +14 more
europepmc   +1 more source

Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification

American Journal of Hematology, EarlyView.
ABSTRACT Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epidemiological studies have found an association between asthma and ACS, but whether this link is causal is ...
Sara El Aouhel, Vanessa Bellegarde, Stennio Da Silva Faria, Tristan St‐Laurent, Estelle Lecluze, Anne‐Laure Pham Hung d’Alexandry d’Orengiani, Frédéric Galactéros, Pablo Bartolucci, Marc‐André Legault, Guillaume Lettre, Thomas Pincez   +10 more
wiley   +1 more source

Real‐World Effectiveness and Safety of Ravulizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria: Evidence From the International PNH Registry

American Journal of Hematology, EarlyView.
ABSTRACT Ravulizumab, a second‐generation complement component 5 inhibitor (C5i) derived from eculizumab, with improved pharmacokinetics, is the current standard‐of‐care treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH), where available.
Alexander Röth, Christopher J. Patriquin, Jeff Szer, Louis Terriou, Ami S. Patel, Jesse Metzger, Philippe Gustovic, Jun‐ichi Nishimura, Robert A. Brodsky   +8 more
wiley   +1 more source

The epidemiology of snakebites, treatment-seeking behaviour, and snakebite management in the department of Ogooué et des Lacs, Gabon, Central Africa: a cross-sectional community and health facility-based survey. [PDF]

J Glob Health
Artus R, Rae J, Hunstig F, Mombo-Ngoma G, Zinsou AH, Okwu DG, Ndoumba WN, Manego RZ, Ramharter M, Lell B, Kremsner PG, Aron MB, Blessmann J, Kreuels B.   +13 more
europepmc   +1 more source

Clinical, Genetic, and Pathologic Variability in Myelodysplastic Syndromes and Precursor Conditions Across Race, Ethnicity, and Sex

American Journal of Hematology, EarlyView.
ABSTRACT The epidemiology of myelodysplastic syndromes/neoplasms (MDS) is challenging to define due to inconsistent reporting, complex diagnostic procedures, and evolving diagnostic criteria. Using the National MDS Natural History Study—a prospective cohort with centrally adjudicated histopathology and genetic variant review—we characterized the ...
Nancy Gillis, Christelle Colin‐Leitzinger, Yi‐Han Tang, Michael Otterstatter, Seth Sherman, Ling Zhang, Lynn C. Moscinski, Mary Ellen Walker, Jeffrey S. Painter, Gregory A. Abel, Tareq Al Baghdadi, H. Joachim Deeg, James M. Foran, Steven D. Gore, Alexandra M. Harrington, Steven H. Kroft, Jane Jijun Liu, Wael Saber, Shamsuddin Virani, Rafael Bejar, R. Coleman Lindsley, Eric Padron, Matthew J. Walter, Rami Komrojki, Amy E. DeZern, Mikkael A. Sekeres   +25 more
wiley   +1 more source

Invasion preferences suggest a possible role for Plasmodium falciparum parasites in the expansion of Duffy negativity in West and Central Africa

Manneh B, Introini V, Reed J, Rotariu M, Antrobus R, Cicuta P, Weekes MP, Penman BS, Rayner JC.   +8 more
europepmc   +1 more source

Interactions between soil and other environmental variables modulate forest expansion and ecotone dynamics in humid savannas of Central Africa. [PDF]

Proc Biol Sci
Sagang LBT, Tcheferi I, Ploton P, Libalah M, Simo-Droissart M, Sirri N, Dauby G, Ngansop E, Bissek JP, Kamdem N, Mofack GII, Zebaze D, Leblanc H, Djonko F, Sonké B, Barbier N, Couteron P.   +16 more
europepmc   +1 more source

The Longitudinal Effect of APOL1 Risk Alleles on Sickle Cell Anemia‐Associated Kidney Function

American Journal of Hematology, EarlyView.
ABSTRACT Progressive kidney injury is a major cause of morbidity and mortality in sickle cell anemia (SCA). The high risk APOL1 G1/G2 variants contribute to the development of kidney disease in individuals of African ancestry, including those with SCA.
Sara R. Rashkin, Guolian Kang, Clifford M. Takemoto, Mitchell J. Weiss, Kenneth I. Ataga, Santosh L. Saraf, Jeffrey Lebensburger, Rima S. Zahr   +7 more
wiley   +1 more source

Editorial: SoTL Conference Special Issue

Araştırma Temelli Etkinlik Dergisi
Bekithemba Dube, Friedrich-Nel Hesta, Zenzile Khetsha, Xolani Khohliso   +3 more
doaj  

Genomic insights into Plasmodium vivax population structure and diversity in central Africa. [PDF]

Malar J
Gartner V, Redelings BD, Gaither C, Parr JB, Kalonji A, Phanzu F, Brazeau NF, Juliano JJ, Wray GA.   +8 more
europepmc   +1 more source