Results 31 to 40 of about 1,794,321 (297)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Biobanking in East and Central Africa: A case of the Integrated Biorepository of H3Africa Uganda [version 1; peer review: 2 approved, 2 approved with reservations]

Open Research Africa, 2022
Biorepositories are essential because they guarantee the proper storage and distribution of biospecimens and their associated data for current and future research.
Lwanga Newton Kigingi, Sharley Melissa Aloyo, Kezimbira Dafala, Nasinghe Emmanuel, Moses L Joloba, Moses Levi Ntayi, David Patrick Kateete, Kamulegeya Rogers, Gideon Nsubuga   +8 more
doaj   +1 more source

Seed Phytosanitary Regulations [PDF]

, 2014
The harmonization of seed policies and regulations in the ASARECA member countries is the first step toward creating a seed market that is large enough to attract investment by local and international investors who will provide the quantity, quality and
Eastern and Central Africa Programme for Policy Analysis
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

DIRECT METAL LASER SINTERING, USING CONFORMAL COOLING, FOR HIGH VOLUME PRODUCTION TOOLING

South African Journal of Industrial Engineering, 2017
Existing techniques to manufacture conventional tool steel inserts for the plastic injection moulding process are expensive and time-consuming. Complex mould inserts, difficult to manufacture with conventional processes, can be produced using Direct ...
van As, Bertus , Combrinck, J. , Booysen, G. J. , De Beer, D. J.   +3 more
doaj   +1 more source

Social Capital and Conflict Management – Lessons Learned and Options for Minimizing Resource Use Conflicts [PDF]

, 2014
Productive and sustainable agriculture can only result from the sustainable utilization and management of the natural resources that carry it. This, however, is usually obstructed by conflicts among intervening decision makers and their different ...
Eastern and Central Africa Programme for Policy Analysis
core  

Global burden of human brucellosis : a systematic review of disease frequency [PDF]

, 2012
BACKGROUND: This report presents a systematic review of scientific literature published between 1990-2010 relating to the frequency of human brucellosis, commissioned by WHO.
A El Sherbini, A Yacoub, AA Haghdoost, Anna S. Dean, B Bonfoh, B Hernandez, E Jelastopulu, E Schelling, Esther Schelling, F De Massis, F Roth, FK Al-Ani, G Marder, G Pappas, GJ Jennings, Helena Greter, Hélène Carabin, I Avdikou, J Ariza, J Zinsstag, J Zinsstag, JA Al Tawfiq, JA Crump, Jakob Zinsstag, KE Elbeltagy, Lisa Crump, M Minas, MA Al Sekait, MA Idris, MR Hosseini, MR Khorasgani, N Gargouri, O Karabay, QM Abu Shaqra, R Awad, S Vancelik, SA Dahouk, SM Alavi, SR Alballa, TJ Doyle, Z Cetinkaya   +40 more
core   +4 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Acceptability of HIV self-testing in African students: a cross-sectional survey in the Democratic Republic of Congo

The Pan African Medical Journal, 2019
INTRODUCTION: The empowerment of young people aged 15-24 years is a key component of an effective AIDS response. HIV self-testing (HIVST) is progressively being implemented in the Democratic Republic of Congo (DRC).
Serge Tonen-Wolyec, Francois-Xavier Mbopi-Kéou, Salomon Batina-Agasa, Ginette Claude Mireille Kalla, Michel Noubom, Ralph-Sydney Mboumba Bouassa, Jean De Dieu Longo, Jérémie Muwonga, Laurent Bélec   +8 more
doaj   +1 more source

Review of Universal Salt Iodation in East Central and Southern Africa (ACSA) [PDF]

, 1997
\ud This paper presents a regional position on Universal Salt Iodation (USI) intervention in 14 countries ill the East, Central and Southern Africa( ECSA) region,namely;Botswana,Kenya,Malawi,Mauritius,Mozambique,Namibia,bells,South Africa, Swaziland ...
Commonwealth Regional Hearth Community Secretariat for East Central and Southern Africa, CRHCS/ECSA
core