Results 161 to 170 of about 612,154 (305)

The forest-hydrology-poverty nexus in Central America : An heuristic analysis [PDF]

A"forest-hydrology-poverty nexus"hypothesis asserts that deforestation in poor upland areas simultaneously threatens biodiversity and increases the incidence of flooding, sedimentation, and other damaging hydrological processes.
Nelson, Andrew, Chomitz, Kenneth M.
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Implementation of an electronic registry to monitor quality of care for febrile episodes in pediatric patients with cancer in Central America and the Caribbean. [PDF]

Support Care Cancer
Levy J, Estripeaut D, Muniz-Talavera H, Chen Y, Bhakta N, Cojulun AC, Badilla KC, Caniza MA, Gonzalez JCC, Rodriquez DJD, Rosalez MAG, Homsi MR, Torres MTL, Melgar M, Vazquez M, Wardell JR, Devidas M, Licona S, Mukkada S.   +18 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A comprehensive review of Onchocercidae nematodes (Nematoda; Filarioidea) infecting wild ruminant ungulates of North and Central America. [PDF]

Int J Parasitol Parasites Wildl
Kulpa M, Verocai GG.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Sapotaceae Family Fruits from Central America: Botanical, Phytochemical and Nutraceutical Insights-A Review. [PDF]

Plants (Basel)
Ibarra-Manzanares ZG, Ibarra-Manzanares AG, Soriano-Melgar LAA, Orozco-Sifuentes MM, Salas-Tovar JA, Rangel-Ortega SDC, Rodríguez-Herrera R.   +6 more
europepmc   +1 more source

Arts for America.

, 1896
Includes art directory and Chicago business references."For the promotion and dispering of good art among the people." -- Cover.Title from cover.Mode of access ...
Central Art Association of America.
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

First Case of Primary Breast Melanoma in Central America: Case Report and Literature Review. [PDF]

Clin Case Rep
García-Urbina A, Espinoza-Vásquez D, Obregón-Silva J, Montoya Rodríguez A.   +3 more
europepmc   +1 more source