Results 101 to 110 of about 10,981,056 (291)

Aortic blood pressure and rate pressure product.

, 2016
Aortic blood pressure parameters of female WT and SRC-1-KO mice. (A) Systolic blood pressure (SBP), (B) Diastolic blood pressure (DBP), (C) Mean blood pressure (MBP), (D) Pulse pressure, (E) Heart rate, and (F) Rate pressure product (RPP).
Antentor Othrell Hinton Jr (3600848), Ann P. Quick (3600842), Yong Xu (17491), Qingchun Tong (307458), Chitra L. Reddy (3600854), Liangru Zhu (3600851), Anilkumar K. Reddy (463834), Jianming Xu (15308), Corey L. Reynolds (741936), Yongjie Yang (3187218), Pingwen Xu (3600839), Xiaofeng Yan (3600845), Xander H. T. Wehrens (389037)   +12 more
core   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source

Pulse wave velocity and central aortic pressure in systolic blood pressure intervention trial participants

PLOS ONE, 2018
Arterial stiffness, typically assessed as the aortic pulse wave velocity (PWV), and central blood pressure levels may be indicators of cardiovascular disease (CVD) risk. This ancillary study to the Systolic Blood Pressure Intervention Trial (SPRINT) obtained baseline assessments (at randomization) of PWV and central systolic blood pressure (C-SBP) to ...
Mark A. Supiano, Laura Lovato, Walter T. Ambrosius, Jeffrey Bates, Srinivasan Beddhu, Paul Drawz, Jamie P. Dwyer, Naomi M. Hamburg, Dalane Kitzman, James Lash, Eva Lustigova, Cynthia M. Miracle, Suzanne Oparil, Dominic S. Raj, Daniel E. Weiner, Addison Taylor, Joseph A. Vita, Reem Yunis, Glenn M. Chertow, Michel Chonchol   +19 more
openaire   +4 more sources

Targeting Nupr1‐Mediated p53 Mitochondrial Sequestration Alleviates Aortic Dissection by Restoring the Gadd45b‐Dependent Survival Program

Advanced Science, EarlyView.
This study identifies Nupr1 as a crucial stress‐responsive orchestrator driving AD. Under severe stress, Nupr1 massively accumulates within mitochondria to sequester p53, triggering apoptosis and concurrently repressing the Gadd45b‐mediated survival program.
Xi Yang, Ke‐Yuan Chen, Yue Tian, Zong‐Sheng Jiang, Jian Lei, Xing‐Hui Zhuang, Jiang‐Bin Wu, Le‐Le Tang, Hao‐Yu Li, Xiao‐Hui Chen, Yue Wang, Yu‐Mei Li, Zhi‐Huang Qiu, Zi‐Wen Cai, Liang‐Wan Chen   +14 more
wiley   +1 more source

Comparison of Risk of Target Organ Damage in Different Phenotypes of Arterial Stiffness and Central Aortic Blood Pressure. [PDF]

Front Cardiovasc Med, 2022
Bai Y, Wang Q, Cheng D, Hu Y, Chao H, Avolio A, Tang B, Zuo J.   +7 more
europepmc   +1 more source

RBMS1 Contributes to Early Arteriovenous Fistula Neointimal Remodeling Through Modulation of VSMC Phenotypic Responses

Advanced Science, EarlyView.
Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li, Chengwei Zhang, Xinying Yu, Shuang Yao, Yiting Lai, Xiaozhu Sun, Yao Zhao, Xiaoyu Lan, Tingting Hu, Wenjin Li, Zhenzhen Ma, Huimin Ma, Zihan Wang, Haihai Liang, Jundong Jiao   +14 more
wiley   +1 more source

Estimating central systolic blood pressure during oscillometric determination of blood pressure:proof of concept and validation by comparison with intra-aortic pressure recording and arterial tonometry

, 2012
Objectives: Central systolic blood pressure is usually estimated by transformation of a peripheral arterial waveform obtained by tonometry and calibrated from conventional measurements of brachial artery blood pressure from a brachial cuff using the ...
Brett, Sally Emma, Chowienczyk, Philip, Guilcher, Antoine, Clapp, Brian   +3 more
core   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

The effects of weight loss using dietary manipulation and rimonabant therapy on arterial stiffness in type 2 diabetes

Artery Research, 2010
Background: Obesity is considered an important factor contributing to premature arterial stiffening in type 2 diabetes but it is uncertain whether weight loss through dietary modification leads to a reduction in arterial stiffness.
A. Chakera, S. Bunce, C. Heppenstall, J.C. Smith   +3 more
doaj   +1 more source

The relationship between 24 hr. central ambulatory blood pressure and arterial stiffness

, 2019
Access to thesis permanently restricted to Ball State community only.The relationship between blood pressure and arterial stiffness is complex and remains incompletely understood. This study aimed to examine the relationship between 24 hr.
Martin, Elizabeth J.
core