Results 71 to 80 of about 292,175 (253)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

International Migration and Social Entrepreneurship: The Role of the Insan-Leilek Foundation in Supporting Migrants from Kyrgyzstan

Halyk̦aralyk̦ k̦atynastar ža̋ne halyk̦aralyk̦ k̦u̇k̦yk̦ seriâsì
The article analyzes the social challenges faced by labor migrants from Kyrgyzstan working in Russia, as well as by their families both in the country of origin and in the host society.
Ж. Нишарапова, А. Оселедко, Е. Чигибаева   +2 more
doaj  

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Central Asia

Following a brief historical overview of how great power competition in Central Asia emerged after the fall of the Soviet Union, this chapter focuses on the contemporary dynamics of the great power competition in the region. Specific attention is paid to the role of Russia, China, the European Union, and the United States as the main great powers ...
  +6 more sources

Missed opportunities for vaccination among healthcare-seeking children: a cross-sectional study in Bishkek, Kyrgyzstan, 2023

BMJ Public Health
Background High vaccination coverage is critical for preventing disease transmission. In Bishkek (population: 1.15 million), childhood vaccination coverage was <90% in 2022. Understanding missed opportunities for vaccination (MOV) at healthcare visits
Aisuluu Kubatova, Roberta Horth, Dinagul Otorbaeva, Gulzada Dadanova, Gulbara Ishenapysova, Dilyara Nabirova   +5 more
doaj   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

THE NEW PIPELINE CONSTRUCTION SUGGESTIONS FROM CENTRAL ASIA TO FAREAST ASIA THROUGH MONGOLIA

Halyk̦aralyk̦ k̦atynastar ža̋ne halyk̦aralyk̦ k̦u̇k̦yk̦ seriâsì, 2016
Қазақстанда балансты сақтау үшін Қытайға жасаған мұнай құбырларын Монғолияға жалғастыру керек. Егер Орталық Азияда осы энергетикалық бизнес жасаса, Қытай Қазақстанда бірінші болуы мүмкін, сонда осы баланс бұзылады. Сондықтан Қазақстанда тыныштық жəне екі
Jung Min Kim
doaj  

Long‐Term Snow Avalanche Trends in High Mountain Asia: Climatic Drivers and Impacts

Earth's Future
Devastating snow avalanches are frequent in High Mountain Asia (HMA) yet remain undocumented with climate change impact drivers poorly understood.
Arnaud Caiserman, Roy C. Sidle, Jakob Steiner, Evgenii Shibkov   +3 more
doaj   +1 more source