Results 41 to 50 of about 6,876,947 (311)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Institutional Arrangement for Macroproprudential Policy – On Differences Across the EU Countries

open access: yesComparative Economic Research, 2018
There is a growing consensus among both economists‑academics and policymakers that there was at least one missing element of the financial safety net during the Global Financial Crisis.
Anna Matysek-Jędrych
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The special account procedure as a technique of central bank control. A study of fifteen years of Australian experience

open access: yesPSL Quarterly Review, 2014
The article assesses the merits of the Special Account procedure as a central banking technique in the light of a detailed study of the Commonwealth Bank’s special account policy over this period.
H.W. ARNDT
doaj   +1 more source

Central bank transparency and cross-border banking [PDF]

open access: yesJournal of International Money and Finance, 2017
Abstract We analyze the effect of central bank transparency on cross-border bank activities. Based on a panel gravity model for cross-border bank claims for 21 home and 47 destination countries from 1998 to 2010, we find strong empirical evidence that a rise in central bank transparency in the destination country, on average, increases cross-border ...
Eichler, Stefan   +2 more
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

BLOCKCHAIN FUTURES IN CRYPTOCURRENCIES, TRADE AND FINANCE: A PRELIMINARY ASSESSMENT

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2020
The study explores whether blockchain technology can change the paradigm of the current financial structure and the balance of power in the international financial system.
Ahmet Faruk Aysan   +2 more
doaj   +1 more source

Central Banking without Romance [PDF]

open access: yesThe European Journal of Comparative Economics, 2018
Many economists, including former Federal Reserve chairman Ben Bernanke, believe that the gold standard generates poor economic outcomes including output volatility, price instability, financial panics, the spread of recessions via the exchange rate, and
Thomas L. Hogan   +2 more
doaj   +1 more source

Centrally Banked Cryptocurrencies

open access: yesProceedings 2016 Network and Distributed System Security Symposium, 2016
Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of scalability and computational cost.
Danezis, George, Meiklejohn, Sarah
openaire   +6 more sources

Central banking in the twenty-first century

open access: yes, 2017
The recent banking crisis has opened up the discourse about central banking. The purpose here is to revisit the principles of central banking and the theoretical framework for applying them in light of these changed conditions.
Dow, Sheila, Sheila Dow
core   +1 more source

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