Results 61 to 70 of about 5,834,193 (401)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Os Bancos Centrais e sua ambivalência público-privada
Nova Economia, 2009 The paper analyzes the historic origin of Central Banks, from three basic processes: the evolution and convergence of the free banking system to a hierarchical and centralized system in the Central Bank; the transformation of Clearing Houses in Central ...
Gentil Corazza
doaj
Central banks and information provided to the private sector
PSL Quarterly Review, 2012 This paper examines the information provided to the private sector by central banks. By using the principal component analysis, we investigated the variance of the procedural rules followed by nine major central banks about informationtreatments.
Giovanni Di Bartolomeo, Enrico Marchetti
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
The central registration of bank credits in France
PSL Quarterly Review, 2014 In France it is quite usual for a firm to have several bankers. This splitting up of loans makes communication between banks particularly necessary, and it is from the initiative of the banks, with the collaboration of the Central Bank and other ...
A. ROUX
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Redefining scientization: Central banks between science and politics
Finance and SocietyThis article introduces a new conceptual framework for examining the transformation of central banks’ activities at the intersection of science and politics.
Aurélien Goutsmedt, Francesco Sergi
doaj +1 more source
Use of distributed ledger technology by central banks: A review
, 2017 This paper reviews what stage the central banks of the world’s leading economies are at in their study and adoption of distributed ledger technology (DLT) to reengineer their various systems and functions.
C. A. D. Río.
semanticscholar +1 more source
Profit Distribution and Loss Coverage Rules for Central Banks
Social Science Research Network, 2016 The issue of central bank profit distribution is both complex and often politically controversial. Based on the replies of 57 central banks worldwide to an ECB questionnaire, this paper analyses how profit distribution rules can affect the amounts ...
D. Bunea +3 more
semanticscholar +1 more source