Results 171 to 180 of about 6,367,918 (301)

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

Canal Boat along the Massillon and Navarre Canal Area 2

One black and white negative of a canal packet boat along the Ohio and Erie Canal near Massillon and Navarre in Stark County, Ohio. The canal can be seen running diagonally across the image while the towpath and the grassy canal bank is visible on the ...
Canal Society of Ohio
core   +1 more source

Three types of ligamentum flavum resections for the treatment of lumbar central canal stenosis: BUTTERFLY retrospective study. [PDF]

Asian Spine J
Kaen A, Romero SR, Romero MJC, Durand F, Martin I.   +4 more
europepmc   +1 more source

State Canal Boat Chas. E. Perkins on Canal

One black and white photographic print of a state canal boat named the Chas. E. Perkins on a canal, probably the Ohio and Erie Canal in eastern Ohio. A portion of the grassy canal bank and a beam crossing the canal can be seen in the foreground while the
Canal Society of Ohio
core  

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

Syringomyelia with Central Canal Enlargement Caused by Postoperative Inflammation after Surgery for Intradural Lumbar Disc Herniation. [PDF]

NMC Case Rep J
Hagizawa H, Moriguchi Y, Yamada T, Kashii M.   +3 more
europepmc   +1 more source

Line of Canal Boats in Unknown Canal Town

One black and white photographic print of a row of canal boats on an unidentified canal, probably the Ohio and Erie Canal in eastern Ohio or the Miami and Erie Canal in western Ohio.
Canal Society of Ohio
core  

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Feasibility of deep learning algorithm in diagnosing lumbar central canal stenosis using abdominal CT. [PDF]

Skeletal Radiol
Jeon Y, Kim BR, Choi HI, Lee E, Kim DW, Choi B, Lee JW.   +6 more
europepmc   +1 more source

Canal Boat on the Hocking Canal 1

One black and white photographic print of a canal boat on the Hocking Canal somewhere in southeastern Ohio. The boat can be seen in the foreground while a bridge can be seen crossing over the canal behind the boat and a hill with trees can be seen in the
Canal Society of Ohio
core