Results 231 to 240 of about 944,652 (357)

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

open access: yesAdvanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu   +17 more
wiley   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

open access: yesAdvanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das   +13 more
wiley   +1 more source

Estrategias de germinación de semillas de 10 plantas herbáceas nativas del matorral esclerófilo de Chile central

open access: yesGayana: Botanica
Se exploró la importancia relativa de la luz y el efecto del frío para la germinación de 10 herbáceas nativas del matorral de Chile central. Las semillas de cada especie fueron asignadas a: (1) semillas germinadas por tres meses bajo luz blanca, no se le
Javier A. Figueroa   +3 more
doaj  

Diversity and Host Relationships of the Mycoparasite Sepedonium (Hypocreales, Ascomycota) in Temperate Central Chile. [PDF]

open access: yesMicroorganisms, 2021
Binimelis-Salazar J   +6 more
europepmc   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

open access: yesAdvanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao   +6 more
wiley   +1 more source

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