This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu +17 more
wiley +1 more source
Leucheriapeteroana (Nassauvieae, Asteraceae), a new species of Leucheria endemic to the Andes of Central Chile, and insights into the systematics of Nassauviae. [PDF]
Lavandero N, Pérez F, Pinilla N.
europepmc +1 more source
Microseismicity Appears to Outline Highly Coupled Regions on the Central Chile Megathrust. [PDF]
Sippl C, Moreno M, Benavente R.
europepmc +1 more source
Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das +13 more
wiley +1 more source
Se exploró la importancia relativa de la luz y el efecto del frío para la germinación de 10 herbáceas nativas del matorral de Chile central. Las semillas de cada especie fueron asignadas a: (1) semillas germinadas por tres meses bajo luz blanca, no se le
Javier A. Figueroa +3 more
doaj
Development and Application of Novel SSR Markers to Assess the Genetic Diversity and Population Structure of <i>Phacelia secunda</i> Along an Altitudinal Gradient in the Central Chile Andes. [PDF]
Torres-Díaz C +5 more
europepmc +1 more source
Diversity and Host Relationships of the Mycoparasite Sepedonium (Hypocreales, Ascomycota) in Temperate Central Chile. [PDF]
Binimelis-Salazar J +6 more
europepmc +1 more source
VARIABILIDAD INTERNA EN EL ALFARERO TEMPRANO DEL CENTRO-SUR DE CHILE: EL COMPLEJO PITRÉN EN EL VALLE CENTRAL DEL CAUTÍN Y EL SECTOR LACUSTRE ANDINO [PDF]
Leonor Adán, Rodrigo Mera Moreno
openalex +1 more source
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao +6 more
wiley +1 more source
Range Extension of the Popeye Catalufa (Pristigenys serrula, Gilbert 1891) to Central Chile During the "El Niño" Southern Oscillation (ENSO) 2023-2024. [PDF]
Asorey CM +3 more
europepmc +1 more source

