Results 261 to 270 of about 944,652 (357)

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Rapid turnover of a pea aphid superclone mediated by thermal endurance in central Chile. [PDF]

Proc Biol Sci
Martel SI, Zamora CA, Ricote N, Sepúlveda DA, Mahéo F, Simon JC, Figueroa CC, Rezende EL, Bozinovic F.   +8 more
europepmc   +1 more source

Hydrological response to land use scenarios under climate change. Adaptation measures for an agricultural basin: Rapel river basin in central Chile.

, 2020
María José González Molina, Haydee Ximena Vargas Mesa, Nicolás Vásquez Placencia   +2 more
openalex   +1 more source

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao, Changxin Zhong, Shilong Jiang, Yungui Li, Yang Xi, Mingxuan Xiao, Ting Jiang, Xiaoya Wan, Zonglin Chen, Xiaohui Yu, Yan Cheng   +10 more
wiley   +1 more source

Assessing Ecogeographic Rules in Two Sigmodontine Rodents along an Elevational Gradient in Central Chile. [PDF]

Animals (Basel)
Valladares-Gómez A, Torres-Pérez F, Palma RE.   +2 more
europepmc   +1 more source

El habitat sustentable de los mercados urbanos historicos. Aplicacion del concepto al Mercado Central de Concepcion, Chile

, 2018
Ana Zazo Moratalla, María Isabel López Meza   +1 more
openalex   +2 more sources

A Novel Co3O4@Co3(HITP)2‐Based Sensor for Low‐Temperatures H2S Detection: Fabrication, Performance, and Preliminary Exploration in Monitoring Pork Spoilage

Advanced Science, EarlyView.
Hybrid Co3O4@Co3(HITP)2‐based chemiresitor was constructed for hydrogen sulfide detection at low‐temperature, which presented excellent sensing performance at room and refrigerant temperature. A proof of concept was conducted by monitoring hydrogen sulfide released from pork spoilage at both temperature using a portable device with a smartphone ...
Yongjiao Sun, Rongrong He, Wuchao Tian, Bingliang Wang, Zhenting Zhao, Zihan Wei, Koichi Suematsu, Wendong Zhang, Kengo Shimanoe, Jie Hu   +9 more
wiley   +1 more source

Molecular detection of Cryptosporidium parvum in wild rodents (Phyllotis darwini) inhabiting protected and rural transitional areas in north-central Chile. [PDF]

Int J Parasitol Parasites Wildl
Carrera-Játiva PD, Acosta-Jamett G, Muñoz P.   +2 more
europepmc   +1 more source

Architectural Heritage at Estacion Central Commune (Chile): Towards a Sustainable Conservation

, 2019
María Victoria Correa Baeriswyl
openalex   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source