Results 121 to 130 of about 61,040 (294)
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao +7 more
wiley +1 more source
Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal +3 more
wiley +1 more source
A pilot study on the influence of biomechanical properties of the cornea on short-term response to myopic corneal refractive therapy [PDF]
The authors state that they do not have any proprietary interest in the products named in this article.To study the short-term corneal response to corneal refractive therapy for myopia and correlate it with corneal biomechanical properties as measured ...
González-Méijome, José Manuel +4 more
core
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani +6 more
wiley +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Central Corneal Thickness and Glaucoma
In routine clinical practice, central corneal thickness, CCT, represents one of several important parameters used not only in the diagnosis of glaucoma but also for following the progression of this disease and its response to treatment. It also has immense clinical impact in planning refractive surgeries.
openaire +1 more source
This Perspective discusses the potential of stimuli‐responsive liquid crystal polymer bio‐interfaces in modulating cell behavior as next generation dynamic artificial scaffolds. Unlike current artificial biomaterials that have static properties, LCPs offer fast, reversible, and spatially programmable deformation that reflects the dynamic properties of ...
Ruth M. C. Verbroekken +2 more
wiley +1 more source
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley +1 more source
The role of central corneal thickness in the diagnosis of glaucoma
Purpose: To determine the effect of central corneal thickness (CCT) on applanation tonometry and any resultant misclassification of normals as ocular hypertension.
Thomas Ravi +2 more
doaj
Corneal power modelling with OCT data – Thin and thick lens paraxial models versus raytracing
Abstract Background Evaluating keratometric power with Zeiss index (PKZ), paraxial thick cornea power (Gullstrand [PG]) and power referenced to the front (PFV) and back vertex plane (PBV) and raytracing power (PR), and modelling the deviation from PKZ with a multivariable linear prediction model.
Achim Langenbucher +4 more
wiley +1 more source

