Results 281 to 290 of about 63,158 (347)

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, Volume 36, Issue 11, 5 February 2026.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Comprehending the Membrane Properties for Emulation in Organs‐on‐a‐Chip

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
The advent of organ‐on‐chip models allows closer emulation of in vivo conditions, leading to effective, less costly, and specific drugs. Although a number of membrane‐based on‐chip models exist, better emulating functional models need to be devised for organ simulations.
Tanmayee Makarand Sathe, Dhananjay Shrikrishna Bodas   +1 more
wiley   +1 more source

Pre‐oviposition development of the brown anole (Anolis sagrei)

Developmental Dynamics, Volume 255, Issue 2, Page 145-167, February 2026.
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling, Natalia A. Shylo, Bonnie K. Kircher, Hannah Wilson, Melainia McClain, Marta Marchini, Katherine B. Starr, Thomas J. Sanger, Florian Hollfelder, Paul A. Trainor   +9 more
wiley   +1 more source

Astrocytic TCF7L2 Impacts Brain Osmoregulation and Restricts Neuronal Excitability

Glia, Volume 74, Issue 2, February 2026.
Astrocytic TCF7L2 impacts extracellular glutamate and glutamine levels. Loss of astrocytic TCF7L2 disrupts extracellular potassium clearance. TCF7L2‐dependent astrocytic changes reduce neuronal excitability. ABSTRACT Astrocytes differentiate and mature during postnatal development, but the molecular mechanisms linking their maturation to neuronal ...
Mariusz Popek, Krzysztof Goryca, Dorota Adamska, Joanna Urban‐Ciećko, Katarzyna Hryniewiecka, Marcin Lipiec, Tomasz Grzegorz Krawczyk, Kamil Rafalko, Alicja Ławicka, Shane A. Liddelow, Lukasz Mateusz Szewczyk   +10 more
wiley   +1 more source

DUSP1 Attenuates Renal Injury in Diabetic Nephropathy by Modulating Ferroptosis: Evidence From Animal Experiments

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Objective Emerging evidence suggests that ferroptosis contributes significantly to the progression of diabetic nephropathy (DN). This study aimed to explore the potential association between dual specificity phosphatase 1 (DUSP1) and ferroptosis in a streptozotocin‐induced DN rat model.
Jiarong Liu, Junping Zhang, Yun Zou, Wen Chen, Jixiong Xu   +4 more
wiley   +1 more source

Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Xi Duan, Run Li, Lei Fu, Jiali Yang, Zhean Zhan   +4 more
wiley   +1 more source

Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine

MedComm, Volume 7, Issue 2, February 2026.
Schematic illustration showing multifunctional hydrogels in the application of tissue engineering and regenerative medicine. ABSTRACT Hydrogels, with excellent hydrophilicity and high‐water content, have emerged as highly versatile biomaterials for tissue engineering and regenerative medicine.
Jieran Lyu, Xuemiao Liu, Qiqi Yang, Yuchang Zhang, Xing Wang   +4 more
wiley   +1 more source

Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu, Zhi‐Ping Jin, Shu‐Qiang Weng, Ji‐Min Zhu, Ling Dong   +4 more
wiley   +1 more source