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Etiologies of central diabetes insipidus in children
Pediatric Neurology, 1994The last major review of the etiologies of central diabetes insipidus in children was performed a quarter century ago, prior to the development of modern neuroimaging techniques. We retrospectively reviewed the records of children with central diabetes insipidus identified at Children's Hospital of Buffalo from 1979 to 1992.
L C, Wang, M E, Cohen, P K, Duffner
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Intracranial calcification in central diabetes insipidus
Pediatric Radiology, 2007Intracranial calcification is a known but extremely rare complication of diabetes insipidus. To date, only 16 patients have been reported and all had the peripheral (nephrogenic) type of diabetes insipidus. We report a child with intracranial calcification complicating central diabetes insipidus.
Salwa Ramadan, Al-Kandari +2 more
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Trauma‐induced central diabetes insipidus in a cat
Australian Veterinary Journal, 2005A 1‐year‐old neutered male domestic shorthair cat presented with a 4‐week history of polydipsia that began immediately after an 8 metre fall. Trauma‐induced central diabetes insipidus was suspected on the basis of the identification of hyposthenuria, normal haematology and serum biochemistry profile and unremarkable abdominal ultrasound examination ...
Campbell, F. E., Bredhauer, B.
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Current Perspective on the Pathogenesis of Central Diabetes Insipidus
Journal of Pediatric Endocrinology and Metabolism, 2005Diabetes insipidus is a heterogeneous condition characterised by polyuria and polydipsia caused by a lack of secretion of vasopressin, its physiological suppression following excessive water intake, or kidney resistance to its action. The clinical and laboratory diagnosis is confirmed by standard tests, but recent advances in molecular biology and ...
GHIRARDELLO S +3 more
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Central diabetes insipidus in children.
Acta Endocrinologica, 1987Abstract. The antidiuretic effect and pharmacokinetics of 10 to 20 μg of intranasal (IN) and 200 to 400 μg of oral (po) 1-deamino-8-D-arginine vasopressin (DDAVP) were studied in 10 paediatric diabetes insipidus patients. A significant increase in urine osmolality was obtained with all doses, maximum within 2 h and still present at 8 h.
Anne Fjellestad-Paulsen +3 more
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Central Diabetes Insipidus in Children and Young Adults
New England Journal of Medicine, 2000Central diabetes insipidus is rare in children and young adults, and up to 50 percent of cases are idiopathic. The clinical presentation and the long-term course of this disorder are largely undefined.We studied all 79 patients with central diabetes insipidus who were seen at four pediatric endocrinology units between 1970 and 1996.
MAGHNIE, MOHAMAD +11 more
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Genetics and diagnosis of central diabetes insipidus
Annales d'Endocrinologie, 2012Most of the central diabetes insipidus cases seen in general practice are acquired but the rare cases of hereditary autosomal dominant or recessive neurohypophyseal diabetes insipidus have provided further cellular understanding of the mechanisms responsible for pre-hormone folding, maturation and release.
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DDAVP in the Treatment of Central Diabetes Insipidus
New England Journal of Medicine, 1976DDAVP, 1-desamino-8-d-arginine-vasopressin, is a synthetic analogue of vasopressin with increased antidiuretic activity and decreased pressor activity. Whereas the antidiuretic-to-pressor ratio of arginine vasopressin is 1, the antidiuretic-to-pressor ratio of DDAVP is 4000.
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Central diabetes insipidus: beware of Langerhans cell histiocytosis!
The Netherlands journal of medicine, 2018Langerhans cell histiocytosis (LCH) is a rare disorder, characterised by a monoclonal proliferation of aberrant histiocytes that accumulate in and infiltrate into different organs. When the hypothalamic-pituitary axis is involved, central diabetes insipidus (CDI) can be its first manifestation.
Brys, A D H +4 more
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