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Neurophysins in Central Diabetes insipidus

Hormone Research, 1996
When they were discovered by Acher and co-workers, neurophysins were thought to act as carriers for the active nonapeptides vasopressin (AVP) and oxytocin (OT) and were then recognized as the inactive fragment of a precursor with a higher molecular weight (propressophysin).
J J, Legros, V, Geenen
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Central Diabetes Insipidus

American Journal of Diseases of Children, 1986
The etiology of diabetes insipidus (DI) was determined in 73 children evaluated from 1962 through 1983. Intracranial tumors produced DI in 34 children, but 27 of these 34 children developed DI only after excision of the tumor. Diabetes insipidus occurred in ten children with intracranial birth defects, eight with severe central nervous system ...
N G, Greger   +3 more
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The Diagnosis of Children with Central Diabetes Insipidus

Journal of Pediatric Endocrinology and Metabolism, 2007
Central diabetes insipidus is the end result of a number of different diseases that affect the hypothalamic-neurohypophyseal system. In many patients, especially children and young adults, it is caused by the destruction or degeneration of neurons that originate in the supraoptic and paraventricular nuclei of the hypothalamus. The known causes of these
GHIRARDELLO S   +3 more
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Etiologies of central diabetes insipidus in children

Pediatric Neurology, 1994
The last major review of the etiologies of central diabetes insipidus in children was performed a quarter century ago, prior to the development of modern neuroimaging techniques. We retrospectively reviewed the records of children with central diabetes insipidus identified at Children's Hospital of Buffalo from 1979 to 1992.
L C, Wang, M E, Cohen, P K, Duffner
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Intracranial calcification in central diabetes insipidus

Pediatric Radiology, 2007
Intracranial calcification is a known but extremely rare complication of diabetes insipidus. To date, only 16 patients have been reported and all had the peripheral (nephrogenic) type of diabetes insipidus. We report a child with intracranial calcification complicating central diabetes insipidus.
Salwa Ramadan, Al-Kandari   +2 more
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Central diabetes insipidus due to sarcoidosis.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2017
We describe a case of a 40-year old Caucasian male who presented with bihilar enlargement. Additional investigation revealed sarcoidosis. During hospitalization patient developed hypernatremia due to central diabetes insipidus. Central diabetes insipidus was caused by neurosarcoidosis.
de Waard, Wolter I. Q.   +2 more
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Central diabetes insipidus in children.

Acta Endocrinologica, 1987
Abstract. The antidiuretic effect and pharmacokinetics of 10 to 20 μg of intranasal (IN) and 200 to 400 μg of oral (po) 1-deamino-8-D-arginine vasopressin (DDAVP) were studied in 10 paediatric diabetes insipidus patients. A significant increase in urine osmolality was obtained with all doses, maximum within 2 h and still present at 8 h.
Anne Fjellestad-Paulsen   +3 more
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Trauma‐induced central diabetes insipidus in a cat

Australian Veterinary Journal, 2005
A 1‐year‐old neutered male domestic shorthair cat presented with a 4‐week history of polydipsia that began immediately after an 8 metre fall. Trauma‐induced central diabetes insipidus was suspected on the basis of the identification of hyposthenuria, normal haematology and serum biochemistry profile and unremarkable abdominal ultrasound examination ...
Campbell, F. E., Bredhauer, B.
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Antidiuretic effect of indapamide in central diabetes insipidus

Acta Endocrinologica, 1990
Abstract. Indapamide produced a significant decrease in urinary output in three patients with central diabetes insipidus. The 24-h urinary volume was reduced from 5 to 2.3 1 in a 39-year-old woman; from 11 to 4.3 1 in a 30-year-old man, and from 16 to 9.2 1 in a 40-year-old man receiving 2.5 mg of indapamide per day.
KOCAK, M, KARADEMIR, BM, TETIKER, T
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DDAVP in the Treatment of Central Diabetes Insipidus

New England Journal of Medicine, 1976
DDAVP, 1-desamino-8-d-arginine-vasopressin, is a synthetic analogue of vasopressin with increased antidiuretic activity and decreased pressor activity. Whereas the antidiuretic-to-pressor ratio of arginine vasopressin is 1, the antidiuretic-to-pressor ratio of DDAVP is 4000.
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