Results 141 to 150 of about 9,120,288 (390)
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Report of the CGIAR Task Force on Central/Eastern Europe and the Former Soviet Union [PDF]
, 1996 Final report of a task force established at ICW95 to assess what, if any, research collaboration the CGIAR should undertake with the 28 countries of Central and Eastern Europe and the former Soviet Union.
CGIAR Task Force on Central/Eastern Europe and the Former Soviet Union
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Monetary transmission mechanism in Central and Eastern Europe: Gliding on a wind of change [PDF]
This paper surveys recent advances in empirical studies of the monetary transmission mechanism (MTM), with special attention to Central and Eastern Europe.
Coricelli, Fabrizio +2 more
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Jewish Women, Identity, and the Aufklärung: The German-speaking Enlightenment around 1800
Central EuropeThis paper poses the question, “how enlightened was German-speaking central Europe around 1800?” The initial idea was to explore how marginalized groups accessed the German Enlightenment.
Josephine Porter
doaj +2 more sources
Observed extreme precipitation trends and scaling in Central Europe
, 2020 J. Zeder, E. Fischer
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source