Results 141 to 150 of about 7,950,860 (300)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Democratic Innovations in Central and Eastern Europe

, 2019
Democratic Innovations in Central and Eastern Europe expands research on democratic innovations by looking specifically at different forms of democratic innovations in Central and Eastern Europe.

core  

“A Leap into the Unknown”

Central Europe, 2019
This article provides insights into the creation of a website analyzing the responses to the Prague Spring designed by the students of East European Studies at the Ludwig Maximilian University of Munich and the University of Regensburg.
Fabian Riesinger, Verena Hesse
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

From Self-Fashioning to State Symbol: Empress Elisabeth's Aesthetic Agency, Posthumous Cult, and National Appropriation in Austria

Central Europe
This thesis interrogates the life and posthumous transformation of Empress Elisabeth of Austria (1837-1898), challenging prevailing historiographical constructions that cast her as a passive consort constrained by the rigid formalities of the Habsburg ...
Sylvia Rutherford
doaj  

Austrian High Enlightenment

Central Europe, 2019
This article examines state building under Joseph II in the Habsburg Empire between the period of 1780-1790 and considers the intellectual successes of Josephinism.
Joshkin Aziz Sezer
doaj  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Kang Youwei on Austria-Hungary

Central Europe
This paper examines a Chinese Intellectual, Kang Youwei's (1858-1927) perspective on the Austro-Hungarian Empire during his visit in the early 20th century, emphasizing the relevance to Kang's proposal to China's modernization.
Nicholas Tsui
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Russification and Russianization in Modern Historiography: Recent Developments and Future Directions

Central Europe
As the Soviet historical archives became accessible to Western scholars beginning in the 1980s, renewed scrutiny was placed on the imperial-colonial policies of the Russian Empire toward its borderlands.
Nicholas W. Sessums
doaj