Results 171 to 180 of about 9,120,288 (390)

Overview Chapter 3: Birth regulation in Europe [PDF]

open access: yes
Early in the 21st century modern contraception -- primarily hormonal methods, advanced IUDs, sterilization and condoms -- has become the main instrument of birth regulation in Northern and Western Europe and gaining ground in Southern Europe and the ...
Tomas Frejka
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The European Central Bank and the Eurosystem [PDF]

open access: yes
The Eurosystem comprises the European Central Bank at its center as well as the national central banks of the twelve countries currently participating in monetary union.
Carol C. Bertaut
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

RECENT REFORMS OF THE URBAN HOUSING SYSTEM IN CENTRAL AND EAST EUROPE [PDF]

open access: yes
The urban housing system in most of Central and East Europe (CEE) is undergoing decentralization, deregulation, and privatization together with other basic changes due to the fall of the iron curtain, the demise of the Soviet Union, and the reinstitution
Thiesenhusen, William C.
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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