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Central Giant Cell Granuloma of the Jaws

2015
Central giant cell granuloma of the jaw is considered a nonneoplastic lesion. It is a benign lesion but sometimes an aggressive osteolytic proliferation consisting of fibrous tissue with osteoclast-like giant cells. The long-term prognosis is good.
María Luisa Paparella   +1 more
openaire   +2 more sources

Genetic Profiling of Central Giant Cell Granuloma of the Jaws

Journal of Craniofacial Surgery, 2005
Central giant cell granuloma (CGCG) of the jaws is a central osteolytic lesion characterized histologically by multinucleated giant cells in a background of ovoid to spindle-shaped mesenchymal cells. Whether CGCG is a reactive lesion or a truly benign neoplasm remains undetermined, and the mechanism determining the onset of the disease remains unknown.
Carinci F.   +10 more
openaire   +5 more sources

Treatment of central giant cell granuloma in children with denosumab

Pediatric Blood & Cancer, 2020
Central giant cell granuloma (CGCG) is a benign but locally aggressive intraosseous lesion of the mandible. Historically, it is treated by curettage or resection.
M. Choe   +6 more
semanticscholar   +1 more source

Central giant cell granuloma or cherubism

Oral Surgery, Oral Medicine, Oral Pathology, 1981
Central osseous tumors, which are radiographically multilocular and have multinucleated giant cells microscopically, present the surgeon and the pathologist with a diagnostic dilemma. In the case presented here the histologic diagnosis of central giant cell granuloma conflicts with the presentation of an atypical case of cherubism.
Thomas R. Kerley, Carl E. Schow
openaire   +3 more sources

Calcitonin therapy for central giant cell granuloma

Journal of Oral and Maxillofacial Surgery, 2003
A number of alternative nonsurgical therapies have been advocated in recent years for the management of the central giant cell granuloma (CGCG). These include calcitonin injections, intralesional steroid injections and subcutaneous alpha-interferon injections.
openaire   +3 more sources

A central giant cell granuloma influenced by pregnancy.

Dentomaxillofacial Radiology, 1997
A case of a 17-year-old patient with exacerbation of a central giant cell granuloma of the mandible during pregnancy is reported. The possible relationship of the giant cell lesion to a pre-existing fibrous dysplasia is considered although there was lack of histological evidence.
T V Disney   +4 more
openaire   +3 more sources

Central Giant Cell Granuloma: A Troublesome Lesion

Journal of Endodontics, 2000
This case reports a central giant cell granuloma, an uncommon but potentially troublesome idiopathic benign lesion. Its radiographic similarity to a routine inflammatory periradicular lesion led to not only delay in diagnosis, but also further delay in successful treatment.
openaire   +3 more sources

Treatment of central giant cell granuloma of the jaw with calcitonin

International Journal of Oral and Maxillofacial Surgery, 1999
Giant cell granuloma of the jaw is a benign lesion that may cause local destruction of bone and displacement of teeth. The common therapy is curettage or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs.
de Lange, J.   +5 more
openaire   +7 more sources

Central giant-cell reparative granuloma

Oral Surgery, Oral Medicine, Oral Pathology, 1969
Abstract A 57-year-old Caucasian woman who had suffered a traumatic injury 39 years previously developed a central giant-cell reparative granuloma which was treated successfully by concomitant endodontic therapy and surgical enucleation. Occasionally this type of lesion may recur, and periodic observation is strongly advised.
openaire   +3 more sources

Central giant cell reparative granuloma of the maxilla

Indian Journal of Otolaryngology, 1978
A case of giant cell reparative granuloma of maxilla is reported because of its rarity in this anatomical location.
P. M. Chaphekar   +3 more
openaire   +2 more sources

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