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Response of Central Giant Cell Granuloma of the Jaw to Imatinib.
Journal of pediatric hematology/oncology, 2022Central giant cell granuloma of the jaw (CGCJ) can be locally aggressive and result in facial and dental deformity. A child with CGCJ was treated surgically and with denosumab with a response but life-threatening toxicity.
Brian Tallent +5 more
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Central giant cell granuloma of the mandible
Journal of Oral and Maxillofacial Surgery, 1983Une observation chez un garcon de 15 ans et discussion de l'etat neoplasique de cette tumeur ainsi que de sa relation avec les lesions ...
Paul Bischoff +2 more
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Oral Surgery, Oral Medicine, Oral Pathology, 1993
The central giant cell granuloma is a tumor that has great potential for the displacement of teeth and the development of a facial deformity. Although its cause and behavior are still matters for discussion, its early diagnosis and treatment are a priority. We describe a patient with a large benign central giant cell granuloma of the anterior mandible.
Brad J. Potter, B.D. Tiner
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The central giant cell granuloma is a tumor that has great potential for the displacement of teeth and the development of a facial deformity. Although its cause and behavior are still matters for discussion, its early diagnosis and treatment are a priority. We describe a patient with a large benign central giant cell granuloma of the anterior mandible.
Brad J. Potter, B.D. Tiner
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Central giant cell granuloma of the mandible
Plastic and Reconstructive Surgery, 1982Although a benign lesion, the central giant cell granuloma can be locally aggressive and quite destructive. The case reported here involved a giant cell lesion occurring in the mandibular symphysis of an 11-year-old girl. The treatment required four hospital admissions over a period of 4 years.
E. L. Granite, George Manstein
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Journal of Oral and Maxillofacial Surgery, 2016
Giant cell nuclear D N A , in 30 giant cell lesions of the jaws, was quantified by computer-assisted image analysis. D N A content was then used to predict clinical behavior and outcome. 4 nuclei in each of 25 giant cells (total = 100 nuclei) were randomly selected and the D N A content was quantified by the Leitz Texture-Analysis-System-Plus ®.
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Giant cell nuclear D N A , in 30 giant cell lesions of the jaws, was quantified by computer-assisted image analysis. D N A content was then used to predict clinical behavior and outcome. 4 nuclei in each of 25 giant cells (total = 100 nuclei) were randomly selected and the D N A content was quantified by the Leitz Texture-Analysis-System-Plus ®.
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Special Care in Dentistry: managing special patients, settings, and situations, 2021
BACKGROUND Central giant cell granuloma (CGCG) is one of the most intriguing lesions of the jaws and its nature has not yet been fully elucidated. Clinically, some CGCG behave more aggressively, while others have an indolent course.
J. D. de Arruda +6 more
semanticscholar +1 more source
BACKGROUND Central giant cell granuloma (CGCG) is one of the most intriguing lesions of the jaws and its nature has not yet been fully elucidated. Clinically, some CGCG behave more aggressively, while others have an indolent course.
J. D. de Arruda +6 more
semanticscholar +1 more source
Cytogenetics of Central Giant Cell Granuloma of the Mandible
Journal of Oral and Maxillofacial Surgery, 2013Central giant cell granuloma is a benign entity that commonly occurs in the mandible and maxilla. It is usually treated by surgical excision, varying from curettage to en bloc resection. Because the entity is more common in diseases such as neurofibromatosis, a genetic element may be involved in its pathogenesis.
Leonid Kachko +3 more
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Pediatric Blood & Cancer, 2021
Recent literature has shown promising results of denosumab as off-label treatment of a central giant cell granuloma (CGCG). 1 In CGCG,thereisanoverproductionofthecytokinereceptoractivatorof nuclear factor- κβ -ligand (RANK-L) by the spindle-shaped ...
K. Brijs +4 more
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Recent literature has shown promising results of denosumab as off-label treatment of a central giant cell granuloma (CGCG). 1 In CGCG,thereisanoverproductionofthecytokinereceptoractivatorof nuclear factor- κβ -ligand (RANK-L) by the spindle-shaped ...
K. Brijs +4 more
semanticscholar +1 more source
Aggressive Central Giant Cell Granuloma of the Mandible
Journal of Oral and Maxillofacial Surgery, 2010An 11-year-old Egyptian boy presented with mild pain in his eft lower jaw accompanied by swelling. Clinical examination howed a hard, tender mandibular enlargement extending rom the chin to the left molar area. The orthopantomogram OPG) showed poorly defined multilocular radiolucency inolving the mandibular body from the right lateral incisor to he ...
Joneja Munish +4 more
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CENTRAL GIANT CELL GRANULOMA OF MAXILLA.
Indian Journal Of Applied ResearchBackground: Central giant cell granuloma are rare non-neoplastic lesions. They are histologically different from giant cell tumour of bone. It contains cellular brous tissue with multiple haemorrhagic foci with aggregates of multinucleated giant cells ...
Tooba Maryam +3 more
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