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THE DIAGNOSIS AND TREATMENT OF CENTRAL GIANT CELL GRANULOMA
The Journal of the American Dental Association, 1997This report reviews the literature involving the central giant cell granuloma. Diagnosis and treatment is presented. The article reports the case of a child who was initially seen in her general dentist's office, then referred to an oral and maxillofacial surgeon.
John B. Roberson+2 more
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Successful denosumab treatment for central giant cell granuloma in a 9-year-old child.
Special Care in Dentistry: managing special patients, settings, and situations, 2021BACKGROUND Denosumab is a nonsurgical treatment option for central giant cell granulomas (CGCG), especially in aggressive lesions. CASE REPORT We describe a 9-year-old girl with an aggressive maxillary CGCG successfully treated with denosumab, avoiding
B. A. Mariz+6 more
semanticscholar +1 more source
Central Giant Cell Granuloma of the Jaws
2015Central giant cell granuloma of the jaw is considered a nonneoplastic lesion. It is a benign lesion but sometimes an aggressive osteolytic proliferation consisting of fibrous tissue with osteoclast-like giant cells. The long-term prognosis is good.
María Luisa Paparella+1 more
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Genetic Profiling of Central Giant Cell Granuloma of the Jaws
Journal of Craniofacial Surgery, 2005Central giant cell granuloma (CGCG) of the jaws is a central osteolytic lesion characterized histologically by multinucleated giant cells in a background of ovoid to spindle-shaped mesenchymal cells. Whether CGCG is a reactive lesion or a truly benign neoplasm remains undetermined, and the mechanism determining the onset of the disease remains unknown.
Carinci F.+10 more
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Central giant cell granuloma or cherubism
Oral Surgery, Oral Medicine, Oral Pathology, 1981Central osseous tumors, which are radiographically multilocular and have multinucleated giant cells microscopically, present the surgeon and the pathologist with a diagnostic dilemma. In the case presented here the histologic diagnosis of central giant cell granuloma conflicts with the presentation of an atypical case of cherubism.
Thomas R. Kerley, Carl E. Schow
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Treatment of central giant cell granuloma in children with denosumab
Pediatric Blood & Cancer, 2020Central giant cell granuloma (CGCG) is a benign but locally aggressive intraosseous lesion of the mandible. Historically, it is treated by curettage or resection.
M. Choe+6 more
semanticscholar +1 more source
Calcitonin therapy for central giant cell granuloma
Journal of Oral and Maxillofacial Surgery, 2003A number of alternative nonsurgical therapies have been advocated in recent years for the management of the central giant cell granuloma (CGCG). These include calcitonin injections, intralesional steroid injections and subcutaneous alpha-interferon injections.
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A central giant cell granuloma influenced by pregnancy.
Dentomaxillofacial Radiology, 1997A case of a 17-year-old patient with exacerbation of a central giant cell granuloma of the mandible during pregnancy is reported. The possible relationship of the giant cell lesion to a pre-existing fibrous dysplasia is considered although there was lack of histological evidence.
T V Disney+4 more
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Acta Odontologica Scandinavica, 2020
Objective Central giant cell granuloma (CGCG) can coexist with other benign lesions of the jaw. These hybrid lesions are diagnostically challenging to both oral pathologists and radiologists. This work systematically reviews the clinical and radiographic
N. Alsufyani+3 more
semanticscholar +1 more source
Objective Central giant cell granuloma (CGCG) can coexist with other benign lesions of the jaw. These hybrid lesions are diagnostically challenging to both oral pathologists and radiologists. This work systematically reviews the clinical and radiographic
N. Alsufyani+3 more
semanticscholar +1 more source
Central Giant Cell Granuloma: A Troublesome Lesion
Journal of Endodontics, 2000This case reports a central giant cell granuloma, an uncommon but potentially troublesome idiopathic benign lesion. Its radiographic similarity to a routine inflammatory periradicular lesion led to not only delay in diagnosis, but also further delay in successful treatment.
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