Are CD68 and Factor VIII-RA Expression Different in Central and Peripheral Giant Cell Granuloma of Jaw: An Immunohistochemical Comparative Study [PDF]
Objective: Central giant cell granuloma and peripheral giant cell granuloma of the jaw and oral cavity are identical in histopathologic features, although they are different in pathogenesis and clinical behavior.
Soudabeh SARGOLZAEİ +2 more
doaj +1 more source
The central giant cell granuloma (CGCG) is an uncommon benign bony lesion that accounts for less than 7% of all benign lesions of the jaws in tooth-bearing areas. Its etiology is unknown and its biological behavior is poorly understood. This condition is a slow-growing, asymptomatic lesion that usually affects children and young adults, predominantly ...
Ustundag, E +3 more
openaire +5 more sources
Clinical management of a peri-implant giant cell granuloma [PDF]
Purpose. Implant therapy plays an important role in contemporary dentistry with high rates of long-term success. However, in recent years, the incidence of peri-implantitis and implant failures has significantly increased.
Carbone, D. +4 more
core +7 more sources
Central giant cell granuloma of the mandible: A perplexing case report
Central giant cell granuloma is an eccentric jaw lesion that mystifies dental profession. Its pathogenicity remains a conundrum and requires differentiation from other similar lesions to develop an effective treatment plan.
Roopashri Govindaraju +2 more
doaj +1 more source
Central giant-cell granuloma in a patient with neurofibromatosis type 1: 7 years of follow-up. [PDF]
Garrido MB +5 more
europepmc +3 more sources
Giant cell nuclear D N A , in 30 giant cell lesions of the jaws, was quantified by computer-assisted image analysis. D N A content was then used to predict clinical behavior and outcome. 4 nuclei in each of 25 giant cells (total = 100 nuclei) were randomly selected and the D N A content was quantified by the Leitz Texture-Analysis-System-Plus ®.
+4 more sources
Aggressive central giant cell granuloma of the mandible: A case report and review of literature
Mandibular aggressive central giant cell granuloma is a rare non-neoplastic giant cell tumour characterised by pain, bone destruction, tooth root resorption, jawbone cortical perforation, and high recurrence rate. This is a case of a 10-year-old boy who
Eziagu UB, Arthur N, Kudamnya IJ
doaj +1 more source
Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases. [PDF]
Denosumab has been used successfully to treat disease-associated osteoclast overactivity, including giant cell tumor of bone. Given its mechanism of action, denosumab is a potent potential treatment of other osteoclast bone dysplasias including central ...
Bernthal, Nicholas M +8 more
core +2 more sources
IL-4 induces the formation of multinucleated giant cells and expression of ?5 integrin in central giant cell lesion [PDF]
It is now well established that IL-4 has a central role in the development of monocytes to multinucleated giant cells (MGCs) by inducing the expression of integrins on the surface of monocytes.
Aghbali, Amirala +5 more
core +1 more source
Salmon calcitonin - a boon in the management of central giant cell granuloma
Central giant cell granuloma is an uncommon, benign, proliferative lesion of unknown etiology, most commonly affecting anterior mandible of younger age group.
D Nivethitha Gangai +1 more
doaj +1 more source

