Results 41 to 50 of about 470,279 (262)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Identification and estimation of bioactive constituents Negundoside, Berberine chloride, and Marmelosin by HPLC and HPTLC for development of quality control protocols for Ayurvedic medicated oil formulation

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background Anu Taila is an ancient medicated oil Ayurvedic preparation that is commonly used for nasya karma. It contains more than 25 herbs and goat milk as per the Ayurvedic Formulary of India (AFI). It strengthens the neck, shoulder, and chest muscles
Ajay Kumar Meena   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Mulberry (Morus spp.): An ideal plant for sustainable development

open access: yesTrees, Forests and People, 2020
Mulberry (Morus spp.) of Moraceae family is regarded as a unique plant on this earth due to its broader geological distribution across the continents; ability to be cultivated in different forms; multiple uses of leaf foliage and its positive impact in ...
Gulab Khan Rohela   +4 more
doaj   +1 more source

Meat myofibril: Chemical composition, sources and its potential for cardiac layers and strong skeleton muscle

open access: yesInternational Journal of Food Properties, 2022
Meat is the richest source of protein and according to meat sources, the protein is composed of different types of amino acids which are completely dependent upon the protein types. Myofibril is basically muscle protein that’s widely present in different
Waseem Khalid   +8 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Strategy Center Study of Regional Area to Center in Conflict of Placement of Ibukota District North Buton

open access: yesJournal of Local Government Issues, 2018
The regional resistance to the center is a permanent issue that faithfully colors the history of the dynamics of central and local relations. This paper is a presentation of research results that try to express the opposition of Local Government to the ...
Laode Muliawan
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Relations Between Central Government and Local Government in Kosovo

open access: yesPrizren Social Science Journal, 2019
This paper represents a model attempt to shed light on institutional relations between two levels of power in the Republic of Kosovo. The wide range of legal acts concerned with the regulation of the reports between Central and Legal Government in Kosovo,
Iliriana BAJRAMI
doaj   +1 more source

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