Results 71 to 80 of about 470,279 (262)

Whether Social Participation Can Affect the Central Government Public Policy Response to the COVID-19 in China. [PDF]

Front Public Health, 2022
Fu L, Sun H, Xu K.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

On New Sequences of $p$-Binomial and Catalan Transforms of the $k$-Mersenne Numbers and Associated Generating Functions

Universal Journal of Mathematics and Applications
In this work, we investigate the binomial transforms and Catalan transform of the $k$-Mersenne and $k$-Mersenne-Lucas numbers and examine the new integer sequences.
Kalika Prasad, Hrishikesh Mahato, Ritanjali Mohanty, Munesh Kumari   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Lead by Relationship: The Behaviors of Relational Leadership in Regional Collaborative Governance

Systems
Leadership lies at the core of public administration, yet research on boundary-spanning leadership has paid limited attention to the micro-level behaviors through which regional collaboration is enacted.
Hua Xing, Lin Luo, Bo Feng
doaj   +1 more source

Groundwater quality variations in Precambrian hard rock aquifers: a case study from Kerala, India

Applied Water Science, 2019
Analytical data of groundwater samples collected from weathered and deep fractured zones in the Precambrian charnockite aquifers in Kerala, India, have been studied to understand their hydrochemical variations and reasons thereof.
P. Nandakumaran, K. Balakrishnan
doaj   +1 more source

Exploring time evolution characteristics of the collaborative mode in emergency information release of public health emergencies: A network analysis of response to COVID-19 from the central government of China. [PDF]

Front Public Health, 2022
Liu J, Song Y, An S, Dong C, Lian C.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source