Results 181 to 190 of about 366,766 (262)

Multi-Omics Data Integration Clustering for Cancer Subtypes Identification Based on Motif High-Order Similarity Graph and Tensor Regularization. [PDF]

Genes (Basel)
Yan H, Hu F.
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

GatorSC: multi-scale cell and gene graphs with mixture-of-experts fusion for single-cell transcriptomics. [PDF]

Brief Bioinform
Liu Y, Zhang Z, Qiu M, Wang S, Salim FD, Shen J, Chen T, Razzak I, Li F, Bian J.   +9 more
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Alteration in cerebral cortex thickness and structural covariance networks in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). [PDF]

Front Neurol
Ren H, Bai W, Ye G, Hong N, Li S, Zhang K, Su H, Luo X, Liu J, Yin F, Suo J, Ren Z, Tian H, Niu X, Zhang M.   +14 more
europepmc   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Centrally symmetric graphs [PDF]

Czechoslovak Mathematical Journal, 1968
openaire   +1 more source

Central Canal Stenosis Severity Does Not Predict Residual Leg Pain After Percutaneous Transforaminal Endoscopic Decompression in Frail Elderly Patients: A Propensity Score-Weighted Cohort Study. [PDF]

J Pain Res
Wang M, Li GZ, Wang FD, Tang L, Zhang H.
europepmc   +1 more source