Results 51 to 60 of about 6,594,395 (276)

Longitudinal Echocardiographic Surveillance of Aortic Dilation in a Phenotype‐Enriched Turner Syndrome Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Turner syndrome (TS) is associated with thoracic aortopathy and increased risk for aortic dissection, yet the natural history of aortic dilation is not well understood. We performed a retrospective longitudinal study of individuals with TS who participated in the TS Society of the United States Healthy Heart Project between 2003 and 2023 ...
Dylan Doerner, Matthew R. Johnson, Sara Mansoorshahi, Rakesh Kathiresan, Katelyn Abel, Jonathan G. You, Emilio Quezada, Siddharth K. Prakash   +7 more
wiley   +1 more source

Diabetes Mellitus Is Associated With Increased Risk for Subsequent Hip Arthroscopy After Index Hip Arthroscopy

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine whether diabetes mellitus is associated with higher systemic and hip‐specific complications and to evaluate reoperation rates after hip arthroscopy. Methods Using the TriNetX Research Network and Current Procedural Terminology and International Classification of Diseases codes, we identified diabetic and nondiabetic patients aged ...
Nicholas J. Morriss, Justin Harrington, Jacob Waldron, Brian Giordano   +3 more
wiley   +1 more source

Effects of Hypothyroidism on Central and Peripheral Atherosclerosis in the Old Aged

, 2019
Objectives:Aging is associated with an increased incidence of thyroid function abnormalities. Thyroid hormones have been shown to affect vascular hemodynamics and arterial stiffness.
Murat Faik Erdoğan, Berna Evranos Öğmen, Teslime Atlı, Volkan Atmış, EVRANOS ÖĞMEN, BERNA, ERDOĞAN, MURAT FAİK, Atlı, Teslime, ATMIŞ, VOLKAN   +7 more
core   +1 more source

Artificial Intelligence Predicts Failure of Nonoperative Treatment in Degenerative Posterosuperior Rotator Cuff Tears

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To develop an artificial intelligence‐based algorithm to predict success of nonoperative treatment in degenerative posterosuperior tears and to identify the most influential features. Methods Patients with degenerative rotator cuff tears initially treated nonoperatively were enrolled prospectively from January 2022 to November 2024.
Santiago Gabardo, Natalia Martínez‐Catalán, José María Belmonte Martínez, Gregorio Bernabé García, José Manuel García Carrasco, Cristina Delgado, María Valencia‐Mora, Gonzalo Luengo‐Alonso, Emilio Calvo   +8 more
wiley   +1 more source

Genetic and Population Analyses Implicate Thyroid‐Related Regulation of RNF144B in Chondrocalcinosis

Arthritis &Rheumatology, EarlyView.
Objective Chondrocalcinosis, characterized by calcium crystal deposition within articular cartilage, affects 5% to 15% of the general population and has recently been identified as an osteoarthritis risk factor. However, its biologic pathways remain unclear.
Yahong Wu, Yanning Xu, Paul C. Okoro, Sirine Saafi, Jard de Vries, Xiaoyi Qi, Edwin H. G. Oei, Sita Bierma‐Zeinstra, Trudy Voortman, David Felson, Joyce B. J. van Meurs, Layal Chaker, J. Mark Wilkinson, Michelle S. Yau, Jessica Bertrand, Cindy G. Boer   +15 more
wiley   +1 more source

Unveiling the hidden: acquired pediatric hypothyroidism

Frontiers in Endocrinology
Acquired hypothyroidism is the most common thyroid disorder in children, with Hashimoto thyroiditis representing the leading cause in iodine-sufficient regions.
Mariacarolina Salerno, Mariacarolina Salerno, Donatella Capalbo, Donatella Capalbo, Mariella Valenzise, Raffaella Di Mase, Letteria Anna Morabito, Chiara Centonze, Malgorzata Gabriela Wasniewska   +8 more
doaj   +1 more source

A Novel Pathogenic IGSF1 Variant in a Patient with GH and TSH Deficiency Diagnosed by High IGF-I Values at Transition to Adult Care

JCRPE, 2023
IGSF1 deficiency is a rare X-linked condition characterized by central hypothyroidism and a wide variety of other clinical features with variable prevalence, including a delayed pubertal testosterone rise and growth spurt in the context of normal or ...
Aslı Derya Kardelen, Esin Karakılıç Özturan, Şükran Poyrazoğlu, Firdevs Baş, Serdar Ceylaner, Sjoerd D. Joustra, Jan M. Wit, Feyza Darendeliler   +7 more
doaj   +1 more source

Central Hypothyroidism With Oxcarbazepine Therapy

Pediatric Neurology, 2006
Abnormalities in thyroid function with the use of several antiepileptic medications are thought to result from increased metabolism of thyroid hormone and interference with the hypothalamic-pituitary axis. Oxcarbazepine was developed to attempt to reduce the side effects that have traditionally been observed with antiepileptic drugs that induce the ...
Department of Pediatrics, Division of Endocrinology, University of Florida College of Medicine, Gainesville, Florida ( host institution ), Miller, Jennifer, Carney, Paul   +2 more
openaire   +3 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Efficacy and Safety of Durvalumab and Tremelimumab in Metastatic Non‐Small Cell Lung Cancer: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA 2020 flow diagram of included studies. ABSTRACT Purpose Immune checkpoint inhibitors have transformed treatment strategies for metastatic non‐small cell lung cancer (mNSCLC). This study aimed to assess the efficacy and safety of durvalumab combined with tremelimumab compared with those of standard chemotherapy, particularly in patients with low ...
Ikhwan Rinaldi, Eric Ricardo Yonatan, Tasia Esterita   +2 more
wiley   +1 more source