Results 121 to 130 of about 17,389,371 (292)

The Past, Present, and Future of Healthcare-Associated Infection Prevention in Pediatrics: Catheter-Associated Bloodstream Infections

, 2010
Central line–associated bloodstream infections cause morbidity and mortality in children. We explore the evidence for prevention of central line–associated bloodstream infections in children, assess current practices, and propose research topics to ...
W. Charles Huskins, Kristina A. Bryant, Aaron M. Milstone, Danielle M. Zerr   +3 more
core   +1 more source

The efficacy of taurolidine lock solution in preventing catheter-related bloodstream infections in pediatrics: a systematic review and meta-analysis

Frontiers in Pharmacology
BackgroundThis systematic review and meta-analysis evaluated the efficacy and safety of taurolidine lock solutions in preventing catheter-related bloodstream infections in pediatric patients with central venous access devices.MethodsThis meta-analysis ...
Congyu Qin, Bingqiang Huang, Zhiqi Liu, Lingling Huang, Huixiu Liao, Jieru Quan, Liwei Li, Xiaomeng Huang, Weiming Liang   +8 more
doaj   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Hospital-Onset Bloodstream Infection Varies by Hospital Location Type

Antimicrobial Stewardship & Healthcare Epidemiology
Objectives: To characterize the incidence and contributing factors related to hospital-onset bloodstream infection (HOBsi) in a nine hospital healthcare system.
Pragya Dhaubhadel, Prasanthi Limgala, Heather Stafford, Mark Shelly   +3 more
doaj   +1 more source

Shared Genetic Pathways Linking Oral Diseases to Gastrointestinal Disorders: An Integrative Multi‐Omics Study

iMetaMed, EarlyView.
Shared genetics pathways connect oral diseases and gut disorders. ABSTRACT Oral diseases are highly prevalent and increasingly recognized as contributors to gastrointestinal disorders. Despite clinical observations of oral–gut comorbidity, the underlying genetic architecture and causal mechanisms remain poorly understood.
Rui Zhang, Yuelan Gao, Yuyang Zhao, Wanyang Zhong, Xingxiang Duan, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection

iMeta, EarlyView.
This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu, Xiuying Tao, Dan Fang, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +5 more
wiley   +1 more source

Evidence-based measures to prevent central line-associated bloodstream infections: a systematic review

Revista Latino-Americana de Enfermagem
Objective: to identify evidence-based care to prevent CLABSI among adult patients hospitalized in ICUs. Method: systematic review conducted in the following databases: PubMed, Scopus, Cinahl, Web of Science, Lilacs, Bdenf and Cochrane Studies ...
Daniele Cristina Perin, Alacoque Lorenzini Erdmann, Giovana Dorneles Callegaro Higashi, Grace Teresinha Marcon Dal Sasso   +3 more
doaj   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye, M. B. Komane, A. P. Manyisane, R. Manganyi   +3 more
wiley   +1 more source

The impact of private equity acquisition of US hospitals on patient outcomes: A systematic review

Journal of Hospital Medicine, EarlyView.
Abstract Background Private equity (PE) firms are increasingly acquiring US hospitals. While PE ownership may infuse capital and managerial expertise, restructuring by organizations with limited patient‐care experience raises safety concerns. The effect of PE ownership on hospital outcomes remains poorly defined.
Angad S. Sidhu, Nikola S. Vuckovic, Salil Gupta, Christopher M. Garcia, Manav B. Patel, Cristiane M. Ueno   +5 more
wiley   +1 more source