Results 61 to 70 of about 17,389,371 (292)

The Effect of Care Bundles Based on Guidelines Over the Central Venous Catheter Infections in an Intensive Care Unit

Türk Yoğun Bakim Derneği Dergisi, 2014
Objective: To detect the effects of care bundle that is prepared depending on guidelines for central line associated infections. Material and Method: Patients in a tertiary medical intensive care unit were followed up during one year period in terms of ...
Ferdi Polat, Ali Haydar Şahinoğlu, Ahmet Dilek, Ersin Köksal, Yasemin Burcu Üstün, Cengiz Kaya, Fatma Ülger, Şaban Esen   +7 more
doaj   +1 more source

Sustained reduction of healthcare-associated infections after the introduction of a bundle for prevention of ventilator-associated pneumonia in medical-surgical intensive care units

Brazilian Journal of Infectious Diseases, 2020
Background: Infection control interventions can be erroneously interpreted if outcomes are assessed in short periods. Also, statistical methods usually applied to compare outcomes before and after interventions are not appropriate for analyzing time ...
Carlos Magno Castelo Branco Fortaleza, Sebastião Pires Ferreira Filho, Marina de Oliveira Silva, Sandra Mara Queiroz, Ricardo de Souza Cavalcante   +4 more
doaj   +1 more source

Central Line–Associated Bloodstream Infection in Neonatal Intensive Care Units [PDF]

Infection Control & Hospital Epidemiology, 2012
Objective.Describe the epidemiology of central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) participating in a standardized and mandatory CLABSI surveillance program.Design.Retrospective cohort.Setting.We included patients admitted (April 2007-March 2011) to 7 level II/III NICUs who developed a CLABSI (as ...
Ana C, Blanchard, Elise, Fortin, Isabelle, Rocher, Dorothy L, Moore, Charles, Frenette, Claude, Tremblay, Caroline, Quach   +6 more
openaire   +2 more sources

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Infection Control Bundles for the Prevention of Hospital Infections [PDF]

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2016
The incidence of hospital-acquired infections increases due to the rising use of invasive procedures and increased length of hospital stay. The incidence of colonization and infection with multidrug-resistant microorganisms also increased along with the ...
Zeynep TÜRE YÜCE, Emine ALP
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Preventing Central Line-Associated Bloodstream Infections (CLABSI)

, 2015
The dominance of central-line-associated bloodstream infection (CLABSI) prevention has become a powerful far-reaching endeavor in recent years. The purpose of this evidence-based practice project is to examine the best practices for preventing central ...
Bernhardt, Courtney
core   +1 more source

Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics

Advanced Science, EarlyView.
This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka, Bushra Raahat, Spyros Tragoudas, Hui Li   +3 more
wiley   +1 more source

Healthcare-associated infection in the Grey’s Hospital paediatric intensive care unit: does an Infection Control Programme work?

Southern African Journal of Infectious Diseases, 2018
Background: Healthcare-associated infections are an important cause of morbidity and mortality globally. Grey’s Hospital introduced an Infection Control Programme in August 2016, which included Best Care Always bundles for reducing the occurrence of ...
Anne L. Armour, Mark E. Patrick, Zelda Reddy, Wilbert Sibanda, Logandran Naidoo, Kevin B. Spicer   +5 more
doaj   +1 more source

Taurolidine–citrate line locks prevent recurrent central line–associated bloodstream infection in pediatric patients

, 2019
This study describes a successful, targeted intervention in central venous access device routine care to decrease central line-associated bloodstream infection.
Tricia Kleidon, Clark, Julia E, Ullman, Amanda, Kleidon, Tricia, Clark, Julia E., Nicolette Graham, Amanda Ullman, Julia E. Clark, Graham, Nicolette   +8 more
core   +1 more source