Results 101 to 110 of about 11,858,997 (304)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Eyrie Student Union; interior; homecoming dance
Students dance at a Central Methodist University (formerly Central College) homecoming dance, located inside the Eyrie Student ...
Central Methodist University, Smiley Memorial Library
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Homecoming parade float; homecoming attendants riding in convertible cars around the football field
Attendants in Central Methodist University (formerly Central College)'s homecoming parade ride in convertible cars around the football field while a team ...
Central Methodist University, Smiley Memorial Library
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Homecoming parade float; Dean Thogmorton and Dean Orschelen riding in a Buick convertible car
Dean Thogmorton and Dean Orschelen riding in a Buick convertible car in a Central Methodist University (formerly Central College) homecoming ...
Central Methodist University, Smiley Memorial Library
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Central Methodist University (formerly Central College) alumni sit in the football bandstand at homecoming. A sign on wall behind reads "Theta Chi Says Fly High Eagles!
Central Methodist University, Smiley Memorial Library
core
, 2004 Mark Anderson hosts Inside central with Jerlyn McIntyre, Bruce Holmquist and mobile planetarium and athletics training equpment featured from 2004.https://digitalcommons.cwu.edu/kcwutv_cwu/1013/thumbnail ...
Central Washington University
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source