Results 91 to 100 of about 723,413 (260)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Academia Nutrition and DieteticsNutrition labeling assists consumers in making informed food choices and promotes essential principles for public health. However, the list of ingredients is not included in its scope.
Mariana V. S. Kraemer +5 more
doaj +1 more source
Central Waste Complex (CWC) Safety Equipment List [PDF]
, 2000 This document lists all safety equipment for the Central Waste Complex, per HNF-PRO-704. This document provides a list of structures, systems, and components that are essential to the continuing safe operation of the Central Waste Complex, as designated by the applicable facility management and the cognizant engineer.
openaire +2 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ergo, An Open Access Journal of PhilosophyAccording to reductivist axiological perfectionism about well-being (RAP), well-being is constituted by the development and exercise of central human capacities.
Hasko von Kriegstein
doaj +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Descriptive Lists of Inscriptions in the Central Provinces and Berar
, 1916 Hira Lal. (1916). Descriptive Lists of Inscriptions in the Central Provinces and Berar. Nagpur: Government Press.
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A List of Land Birds from Central and Southeastern Washington
The Auk, 1904 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +2 more sources