Results 11 to 20 of about 258 (106)

A randomized phase II trial of gemcitabine, nab-paclitaxel, cisplatin with or without a medically supervised ketogenic diet for patients with metastatic pancreatic cancer. [PDF]

Cancer
ABSTRACT Background A randomized phase II screening trial of gemcitabine, nab‐paclitaxel, and cisplatin with a medically supervised ketogenic diet (MSKD) versus usual diet (non‐MSKD) was conducted in patients with treatment‐naive metastatic pancreatic ductal adenocarcinoma (PDAC).
Jameson GS, Roe DJ, Borazanci E, Hanna DL, Roberts CGP, Pelster MS, Frank RC, Alistar AT, Miller AM, Wiedmeier-Nutor JE, Algaze SD, Zoller AR, Hallberg SJ, Wertheim BC, Lee K, Cridebring D, Rabinowitz JD, Gately S, Keppler J, Sharma S, Von Hoff DD, Rasco DW.   +21 more
europepmc   +2 more sources

Effect of Eplontersen in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy Across Genetic Variants: An Exploratory Analysis From the NEURO-TTRansform Trial. [PDF]

Eur J Neurol
In this exploratory analysis of the NEURO‐TTRansform Phase 3 trial, the efficacy of eplontersen was evaluated in patients with early‐ or late‐onset Val30Met (p.Val50Met) or non‐Val30Met hereditary transthyretin amyloidosis with polyneuropathy. Eplontersen halted neuropathy impairment as measured by the mNIS+7 composite score and improved Norfolk QoL‐DN
Gillmore JD, Adams D, Weiler M, Masri A, Obici L, Nåtman J, Kwoh TJ, Reicher B, Revkin J, Cruz MW, Gertz M, Chao CC.   +11 more
europepmc   +2 more sources

Untargeted Metabolomics Reveals Organ-Specific and Extraction-Dependent Metabolite Profiles in Endemic Tajik Species <i>Ferula violacea</i> Korovin. [PDF]

Plant Direct
ABSTRACT Ferula violacea Korovin, an endemic Tajikistani plant with purported medicinal properties, remains understudied. This study employs untargeted metabolomics to characterize the metabolite profiles of ethanol extracts and juices from F. violacea roots and seeds.
Mavlonazarova S, Acosta K, Abzalimov R, Satorov S, Dushenkov V.   +4 more
europepmc   +2 more sources

Molecular investigation of the phylogenetic placement of Kartalinia and a revision of Bituminaria (Fabaceae: Psoraleeae)

TAXON, Volume 75, Issue 4, August 2026.
Abstract The genus Kartalinia was described to accommodate a single, obscure species, Psoralea acaulis, based on its unique morphology and karyology. No concerted molecular phylogenetic studies were available for this species at the time, and therefore its phylogenetic position was uncertain.
Brian Du Preez, Salvatore Brullo, Charles H. Stirton, Salvatore Cambria, A. Muthama Muasya   +4 more
wiley   +1 more source

The SWITCH algorithm: An expert consensus on treat‐to‐target criteria for chronic prurigo

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1185-1194, July 2026.
The SWITCH project assessed patients' most distressing symptoms and therapy goals, followed by an expert‐based consensus procedure to define T2T criteria for patients with chronic prurigo (CPG)/prurigo nodularis. Based on these validated criteria, a 4‐step SWITCH algorithm was established to enhance CPG therapy outcomes and reduce patient burden ...
Lea S. Stahl, Claudia Zeidler, Joyce Loewenthal, Svenja Royeck, Matthias Augustin, Robert Bissonnette, Sarina Elmariah, Brian S. Kim, Laurent Misery, Hiroyuki Murota, Hong Liang Tey, Elke Weisshaar, Gil Yosipovitch, Franz J. Legat, Adam Reich, Martin Metz, Sonja Ständer   +16 more
wiley   +1 more source

The cost of dementia in the United States in 2026

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Comprehensive cost measurement is essential for an effective policy response to societal dementia costs. METHODS Using dynamic microsimulation, the Health and Retirement Study, and other national data, we quantified the 2026 cost of dementia in the United States. RESULTS In 2026, 5.7 million (95% confidence interval [CI] [5.6, 6.0]
Johanna Thunell, Bryan Tysinger, Matthew Baumgart, Maria Carrillo, Eileen Crimmins, Dana Goldman, Hanke Heun‐Johnson, Mireille Jacobson, Geoff Joyce, Duncan Leaf, Lycia Tramujas Vasconcellos Neumann, Julie Zissimopoulos   +11 more
wiley   +1 more source

Bridging research, policy, and practice: Advancing evidence‐informed approaches for dementia care and prevention: An expert review by the Health Policy Professional Interest Area from ISTAART

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract Bridging dementia research and policy remains a global challenge, with gaps in governance, capacity, data infrastructure, and contextual fit limiting the development and implementation of effective national dementia plans. To inform this issue, the Health Policy Professional Interest Area of the International Society to Advance Alzheimer's ...
Juliana Souza‐Talarico, Maria M. Pinzon, Jayalakshmi Viswanathan, Tuan Anh Nguye, Walter D. Dawson, Jay Lusk, Crystal Glover, Perlina Desai, Anna Shelander, Lesley E. Williamson, Dallas Seitz, Joseph M. Costello, Magdalena Pereyra, Yixuan Cheng, Sharon Naismith, Andrea Slachevsky, Lycia Tramujas Vasconcellos Neumann, Preeti Pushpalata Zanwar   +17 more
wiley   +1 more source

Mitigating disparities in diagnosis of dementia

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract The field of Alzheimer's disease and related dementias (AD/ADRD) is undergoing a transformative shift with a better understanding of disease biology, biomarker‐based diagnostics, and disease‐modifying therapies. Yet, these advancements risk exacerbating existing disparities in diagnosis and care.
Lycia Tramujas Vasconcellos Neumann, Simin Mahinrad, Erin Abner, Soo Borson, Goldie S. Byrd, Maria C. Carrillo, Lindsay Clark, Anthony N. Correro II, Kacie D. Deters, Peggye Dilworth‐Anderson, Rebecca M. Edelmayer, Jason D. Flatt, Crystal M. Glover, Joshua D. Grill, Carl V. Hill, Thomas K. Karikari, Fred B. Ketchum, Emily A. Largent, Jennifer H. Lingler, Jose A. Luchsinger, Gladys E. Maestre, Michelle M. Mielke, Sid O'Bryant, Ozioma C. Okonkwo, Monica W. Parker, Annalise M. Rahman‐Filipiak, Rema Raman, Suzanne E. Schindler, Jose Soria Lopez, Shana D. Stites, Astrid M. Suchy‐Dicey, Whitney Wharton, Rachel A. Whitmer, Lisa Ann Kirk Wiese, Charles C. Windon, Amy Kind, Lisa L. Barnes   +36 more
wiley   +1 more source

A new phylogeny and phylogenetic classification for Solanaceae

TAXON, Volume 75, Issue 2, April 2026.
Abstract Solanaceae are a globally distributed family of considerable economic importance. Recent phylogenetic work on various clades in the family has resulted in a plethora of names at various taxonomic levels. This results in a confusing set of names applied to clades at different ranks, and to the use of informal names that are often not accepted ...
Rocío Deanna, Gloria E. Barboza, Lynn Bohs, Steven Dodsworth, Edeline Gagnon, Leandro L. Giacomin, Sandra Knapp, Andrés Orejuela, Peter Poczai, Tiina Särkinen, Stacey D. Smith, Richard G. Olmstead   +11 more
wiley   +1 more source

Two Southern Hemisphere species on two continents, one rarely collected, one undescribed, form a moth family without hearing organs (Lepidoptera, Geometroidea, Apoprogonidae stat. rev.)

Systematic Entomology, Volume 51, Issue 2, April‐June 2026.
The systematic placement of the South African Apoprogones hesperistis Hampson and southern South American Ona australis gen. et sp. n. has been controversial. Based on mitogenomes, phylogenomic data and morphological evidence, we classify both taxa to the moth family Apoprogonidae stat. rev., whose members lack abdominal hearing organs.
Pasi Sihvonen, Niklas Wahlberg, Etka Yapar, Leidys Murillo‐Ramos, Hermann S. Staude, Max Söderholm, Gunnar Brehm, Axel Hausmann, Hossein Rajaei, Jannik Wagner, Kyung Min Lee   +10 more
wiley   +1 more source