Results 131 to 140 of about 6,838,104 (166)
Ricardo Alexandre Stock, Daiane Karen Galvan, Rafael Godoy, Elcio Luiz Bonamigo Universidade do Oeste de Santa Catarina, Joaçaba, Santa Catarina, Brazil Purpose: To analyze, using optical coherence tomography, the macular thickness values of ...
Godoy R +3 more
core
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Yenny Angela +6 more
wiley +1 more source
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li +23 more
wiley +1 more source
ABSTRACT Background and Aims This study was designed to evaluate the safety, efficacy, and durability of suprachoroidal triamcinolone acetonide, administered either alone or in combination with intravitreal bevacizumab (IVB), in the treatment of diabetic macular edema (DME). Methods This prospective comparative interventional study was conducted in the
Muhammad Tahir Ghaffar +6 more
wiley +1 more source
Quantitative analysis of macular thickness following uneventful and complicated cataract surgery
Betül Ilkay Sezgin Akçay, Tahir Kansu Bozkurt, Esra Güney, Cihan Ünlü, Gürkan Erdogan, Gülünay Akcali, Huseyin BayramlarUmraniye Research and Training Hospital, Istanbul ...
Akçay Bİ +6 more
core
Use of antivascular endothelial growth factor for diabetic macular edema
Rushmia Karim, Benjamin TangUniversity of Sydney School of Public Health, Concord Repatriation General Hospital, Concord, NSW, AustraliaBackground: Diabetic macular edema (DME) is one of the manifestations of diabetic retinopathy leading to loss of ...
Rushmia Karim, Benjamin Tang
doaj
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li +6 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Aleksandra Leoniuk,1 Katarzyna Ptaszynska,2 Anna Szwedowicz,1 Emilia Sawicka-Smiarowska,2 Remigiusz Kazimierczyk,2 Agnieszka Zonenberg,1 Barbara Pieklarz,1 Daniel Baldyga,1 Iwona Obuchowska,1 Joanna Konopinska,1 Karol A Kaminski,2 Diana A Dmuchowska1 ...
Leoniuk A +11 more
doaj
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley +1 more source

