Results 141 to 150 of about 38,605 (289)

Convergent effects of neuropeptides on the feeding central pattern generator of Aplysia californica.

open access: yesJ Neurophysiol, 2022
Due MR   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Modeling and Simulation of Hexapod Kinematics with Central Pattern Generator

open access: yes, 2016
The revealed secrets of nature always led humans to their aspiring achievements. The fastest animal on land is Cheetah and similar robot has developed by engineers so far to attain a record speed of 20mph among legged robots. But in nature there are some
M.T., Aju
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Low Power CMOS Electronic Central Pattern Generator Design for a Biomimetic Underwater Robot

open access: yes, 2008
— This paper, presents a feasability study of a central pattern generator-based analog controller for an autonomous robot. The operation of a neuronal circuit formed of electronic neurons based on Hindmarsh-Rose neuron dynamics and first order chemical ...
Kyung Ki Kim   +5 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

VERTICAL CENTER OF MASS MOTION GENERATION METHOD USING EVOLUTIONARY OPTIMIZED CENTRAL PATTERN GENERATOR FOR HUMAN-LIKE STABLE BIPEDAL WALKING

open access: yes, 2013
본 발명은 안정적인 이족 보행을 위해 진화 최적화된 중앙 패턴 생성기를 이용한 수직 방향의 무게 중심 움직임 생성 방법에 관한 것으로, 진화 최적화된(evolutionary optimized) 중앙 패턴생성기(central pattern generator, CPG)를 이용하여 수직 방향의 무게 중심 움직임을 생성하는 (a) 단계;를 포함하는 것을 특징으로 한다.상기와 같은 본 발명에 따르면, 진화 최적화된(evolutionary optimized ...
홍영대, 김종환, 박창수
core  

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