Results 141 to 150 of about 8,000,685 (282)

Eyrie Student Union; interior; homecoming dance

open access: yes
Students dance at a Central Methodist University (formerly Central College) homecoming dance, located inside the Eyrie Student ...
Central Methodist University, Smiley Memorial Library
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Homecoming parade float; homecoming attendants riding in convertible cars around the football field

open access: yes
Attendants in Central Methodist University (formerly Central College)'s homecoming parade ride in convertible cars around the football field while a team ...
Central Methodist University, Smiley Memorial Library
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Homecoming parade float; Dean Thogmorton and Dean Orschelen riding in a Buick convertible car

open access: yes
Dean Thogmorton and Dean Orschelen riding in a Buick convertible car in a Central Methodist University (formerly Central College) homecoming ...
Central Methodist University, Smiley Memorial Library
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Homecoming; alumni sitting in the football bandstand; sign on wall behind reads "Theta Chi Says Fly High Eagles!"

open access: yes
Central Methodist University (formerly Central College) alumni sit in the football bandstand at homecoming. A sign on wall behind reads "Theta Chi Says Fly High Eagles!
Central Methodist University, Smiley Memorial Library
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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