Results 111 to 120 of about 21,714 (253)

Precocious Puberty : Clinical and Endocrine Profile and Predictors of Neurogenic Etiology in Girls with Central Precocious Puberty [PDF]

, 2012
INTRODUCTION: Puberty is characterized by the appearance of secondary sexual features and transition from the sexually immature form to the sexually mature form.
Srinivasan, P
core  

[Central precocious puberty].

Endokrynologia Polska, 2009
Central precocious puberty, defined as the onset of puberty before the age 8 years in girls and 9 years in boys, results from a premature activation of gonadotropin-releasing hormone neurons in the hypothalamus. This condition is characterised by early pubertal changes, acceleration of growth velocity, and rapid bone maturation that often result in ...
Robert, Krysiak, Bogdan, Marek, Bogusław, Okopień   +2 more
openaire   +1 more source

Central precocious puberty and risk of atopic diseases: The mediating role of obesity and sex hormones

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
Abstract Background Atopic diseases, including atopic dermatitis, allergic rhinitis, and asthma, are complex inflammatory conditions with increasing prevalence in children. Central precocious puberty (CPP) has also become increasingly common. The potential role of CPP in atopic diseases remains unclear.
Yung‐Han Lai, Yu Hsiang Liu, Hsiao‐Chi Chuang, Nguyen Thi Kim Anh, Hsin‐Yuan Chang, Yang‐Chin Chen   +5 more
wiley   +1 more source

Idiopathic Central Precocious Puberty Associated with 11 Mb De Novo Distal Deletion of the Chromosome 9 Short Arm

Case Reports in Genetics, 2013
We report a girl with a de novo distal deletion of 9p affected by idiopathic central precocious puberty and intellectual disability. Genome-wide array-CGH revealed a terminal deletion of about 11 Mb, allowing to define her karyotype as 46; XX, del(9)(p23-
Mariangela Cisternino, Erika Della Mina, Laura Losa, Alexandra Madè, Giulia Rossetti, Lorenzo Andrea Bassi, Giovanni Pieri, Baran Bayindir, Jole Messa, Orsetta Zuffardi, Roberto Ciccone   +10 more
doaj   +1 more source

Precocious and Early Central Puberty in Children With Pre-existing Medical Conditions: A Single Center Study

Frontiers in Pediatrics, 2019
Background: Precocious and early puberty are reported findings in children with pre-existing medical conditions including certain syndromes. Series pertaining to such situations are limited.Methods: A retrospective, single-center study was conducted on ...
Sarah Winter, Adélaïde Durand, Raja Brauner   +2 more
doaj   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, Volume 13, Issue 29, 22 May 2026.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model

Annals of Neurology, Volume 99, Issue 5, Page 1287-1302, May 2026.
Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins, Philip H. Iffland II, John Page, Rebecca Z. Flessner, Soad M. Elziny, Irina Sbornova, Janice K. Babus, Sophie R. Bruckmeier, Ria Parikh, Merel Verhoeven, James Fasham, Joseph S. Leslie, Richard Caswell, Nishanka Ubeyratna, Olivia Wenger, Ethan M. Scott, John Schreiber, Steffen Syrbe, Annick Klabunde‐Cherwon, Martina Owens, Andrew H. Crosby, Emma L. Baple, Peter B. Crino, the KPTN Consortium, Andrea Seeley, Heather Rocha, Sabine Rudnick, Ulrich Schaatz, Tobias Haack, Eva Schwaibold, Caleb Bupp, Klaas Wierenga, John Schreiber, Thorkild Terkelsen, Sarina Kant, J. C. Herkert, Michael Wright, Boris Keren, Solveig Heide, Pamela Jackson, Pradeep Vasudevan, Helen Stewart, Perrine Charles, Andreas Hahn, Saskia Biskup, Inger‐Lise Mero, Martin Heier, Conny van Ravenswaaij‐Arts, Esther Nibbeling, Stephanie Efthymiou, Erum Afzal, Ian Ellis, Raza Maroofian, Almundher Al‐Maawali, David Coman, Anthony Morosini, Sajjad Biglari, Pooneh Nikuei, Saadet Mercimek‐Andrews, Prab Prabhakar, Raymond Louie, Kameryn Butler, Olivia Wenger, Ethan M. Scott, Andrea Seeley, Heather Rocha, Amber Begtrup, Sabine Rudnik, Ulrich Schatz, Tobias Haack, Eva Schwaibold, Caleb Bupp, Klaas Wierenga, John Schreiber, Thorkild Terkelsen, Sarina Kant, J. C. Herkert, Michael Wright, Boris Keren, Solveig Heide, Pamela Jackson, Pradeep Vasudevan, Helen Stewart, Perrine Charles, Andreas Hahn, Saskia Biskup, Inger‐Lise Mero, Martin Heier, Marijn Stokman, Conny van Ravenswaaij‐Arts, Esther Nibbeling, Stephanie Efthymiou, Erum Afzal, Kristina Zhelcheska, Henry Houlden, Ian Ellis, Reza Maroofian, Gholamreza Shariati, Hamid Galehdari, Almundher Al‐Maawali, Adila Al‐Kindi, Andrew Y. Shuen, Victoria Siu, Annick Klabunde‐Cherwon, Steffen Syrbe   +104 more
wiley   +1 more source

Imaging Findings and Prevalence of Central Precocious Puberty at Siriraj Hospital

Siriraj Medical Journal, 2003
Central precocious puberty occurs as a result of premature pituitary stimulation and increased secretion of gonadotropins. The differential diagnosis of true precocious puberty includes cerebral and idiopathic categories.
Sopa Pongpornsup, Orasa Chawalparit, Preeyacha Pacharn   +2 more
doaj  

Central Precocious Puberty in Cerebral Palsy

, 2015
Children affected by cerebral palsy (CP) could experience central precocious puberty (CPP) 20 times more than general population.
PREDIERI, Barbara, BRUZZI, Patrizia, De Luca, Filippo, BARTOLI, ALESSANDRA, Messina, Maria Francesca, IUGHETTI, Lorenzo, Lucaccioni, Laura   +6 more
core  

Adopted girls with idiopathic central precocious puberty: observations about character.

, 2004
The aim of this study was to investigate the psychological traits of adopted girls affected by idiopathic central precocious puberty (ICPP). Twelve adopted girls were evaluated before, during GnRH agonist (GnRHa) treatment, and after the treatment was ...
CAPALBO, DONATELLA, Ferri P., Officioso A., SALERNO, MARIACAROLINA, Muzzica S., Esposito V.   +5 more
core   +1 more source