Results 101 to 110 of about 1,548,347 (335)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Fast Collision Detection Method with Octree-Based Parallel Processing in Unity3D

Engineering Proceedings
Performing accurate and precise collision detection is a key to real-time applications in computer graphics, games, physical-based simulation, virtual reality, augmented reality, and research and development.
Kunthroza Hor, Taeheon Kim, Min Hong
doaj   +1 more source

Central processing unit based on cascade straight heat pipe

IOP Conference Series: Materials Science and Engineering, 2019
Abstract Smart technologies are the scientific knowledge application that develops into computer technology. Central Processing Unit (CPU) is a computer hardware that carries out the computer program instructions. The CPU technology development is very fast with the impression of smaller dimensions yet maintain its performance and ...
W N Septiadi, I G A A D Wulandari, W A W Ula, I A Tnunay, I K G Wirawan, M R Murti, N Putra   +6 more
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Central processing unit of IEC 61131-3-based PLC

IFAC-PapersOnLine, 2016
Abstract: The article discusses the design process of the central processing unit (CPU) for programmable logic controllers. On the one hand the designed CPU is compatible with IEC 61131-3 standard. On the other hand, the authors attempt to reflect on the possible implementations of the unit by means of FPGA.
Przemyslaw Mazur, Miroslaw Chmiel, Robert Czerwinski   +2 more
openaire   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Subsystem design package for Mod 2 site data acquisition system: Solar heating and cooling [PDF]

The Mod II Site Data Acquisition Subsystem (SDAS) is designed to collect data from sensors located on residential or commercial buildings using a solar heating and/or cooling system.

core   +1 more source

An efficient quantum circuit implementation of Shor’s algorithm for GPU accelerated simulation

AIP Advances
In this study, we introduce a novel implementation of Shor’s algorithm specifically designed for the Graphics Processing Unit (GPU) acceleration framework.
XinJian Tan, Peng Gao
doaj   +1 more source