Results 141 to 150 of about 1,548,347 (335)
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Comparision of graphics processing units and central processing units
, 2009 Graphic processors are becoming faster and faster. Computational power within graphic processing units (GPUs) is growing rapidly compared to central processing units (CPUs). Usage of this power is becoming very interesting in many areas. Programmers try to use this power. They are developing new algorithms for non-graphic applications.
openaire +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Vector computer memory bank contention [PDF]
A number of vector supercomputers feature very large memories. Unfortunately the large capacity memory chips that are used in these computers are much slower than the fast central processing unit (CPU) circuitry.
Bailey, D. H.
core +1 more source
Безопасность информационных технологий, 2016 The results of implementation of pilot-project to test IBM Big Data platform for automation of processes of collection, processing and analysis of unstructured big data applied to the individual functional unit of the banking supervision of the Central ...
Sergey Vladimirovich Zapechnikov +4 more
doaj
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
On the Sojourn Time Distribution in a Finite Population Markovian Processor Sharing Queue
, 2013 We consider a finite population processor-sharing (PS) queue, with Markovian arrivals and an exponential server. Such a queue can model an interactive computer system consisting of a bank of terminals in series with a central processing unit (CPU).
Knessl, Charles +2 more
core
Many-body computing on Field Programmable Gate Arrays
Communications PhysicsImproving many-body computational efficiency is crucial for exploring condensed matter systems. However, existing acceleration methods are limited and mostly based on von Neumann-like architectures. Here we leverage the capabilities of Field Programmable
Songtai Lv +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source