Results 61 to 70 of about 304,090 (304)

Research on Hardware-in-the-loop Simulation for Traction Drive System of EMUs

机车电传动, 2018
The performance of traction control unit (TCU) directly affects the stability, dynamic response and speed range of EMUs. In order to realize the optimal design and comprehensive verification of TCU, the hardware-in-the-loop (HIL) of traction drive system
ZHAO Leiting, ZHAO Zhen, JIANG Wei, LI Xinghua   +3 more
doaj  

Parallel genome-wide analysis with central and graphic processing units [PDF]

2015 IEEE International Conference on Computer and Communications (ICCC), 2015
The Indonesia Colorectal Cancer Consortium (IC3), the first cancer biobank repository in Indonesia, is faced with computational challenges in analyzing large quantities of genetic and phenotypic data. To overcome this challenge, we explore and compare performance of two parallel computing platforms that use central and graphic processing units.
Muhamad Fitra Kacamarga, James W. Baurley, Bens Pardamean   +2 more
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Scalable and lightweight deep learning for efficient high accuracy single-molecule localization microscopy

Nature Communications
Deep learning has significantly improved the performance of single-molecule localization microscopy (SMLM), but many existing methods remain computationally intensive, limiting their applicability in high-throughput settings. To address these challenges,
Yue Fei, Shuang Fu, Wei Shi, Ke Fang, Ruixiong Wang, Tianlun Zhang, Yiming Li   +6 more
doaj   +1 more source

Produced water treatment and recovery in the oil and gas industry: A bibliometric analysis from 1977 to 2024

Cleaner and Responsible Consumption
Produced water, generated as a byproduct of oil and gas extraction, is a complex mixture characterized by high salinity and the presence of hydrocarbons, heavy metals, salts, and production-related chemicals.
Abdulaziz M. Al-Abdulla, Nafis Mahmud, Sabla Y. Alnouri, Muftah H. El-Naas   +3 more
doaj   +1 more source

Survey of deployment locations and underlying hardware architectures for contemporary deep neural networks

International Journal of Distributed Sensor Networks, 2019
This article overviews the emerging use of deep neural networks in data analytics and explores which type of underlying hardware and architectural approach is best used in various deployment locations when implementing deep neural networks. The locations
Miloš Kotlar, Dragan Bojić, Marija Punt, Veljko Milutinović   +3 more
doaj   +1 more source

Z8001-based central processing unit with capability addressing

Electronics Letters, 1982
A central processing unit has been implemented, based on a Zilog Z80001 microprocessor and other off-the-shelf chips. The main features are a capability scheme for the protection of information and an effective hardware support for context switching from one process to another. The letter describes the overall CPU design with special reference to these
CORSINI P, LOPRIORE, LANFRANCO
openaire   +4 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source