Results 61 to 70 of about 1,548,347 (335)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Entropy, 2019 This paper presents new results in implementation of parallel computing in modeling of fractional-order state-space systems. The methods considered in the paper are based on the Euler fixed-step discretization scheme and the Grünwald-Letnikov ...
Rafał Stanisławski, Kamil Kozioł
doaj +1 more source
Retinoblastoma protein: a central processing unit
Journal of Biosciences, 2009 The retinoblastoma protein (pRb) is one of the key cell-cycle regulating proteins and its inactivation leads to neoplastic transformation and carcinogenesis. This protein regulates critical G1 -to-S phase transition through interaction with the E2F family of cell-cycle transcription factors repressing transcription of genes required for this cell-cycle
openaire +2 more sources
The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore–microtubule coupling unit [PDF]
, 2023 Amit Rahi +7 more
openalex +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Random Access in C-RAN for User Activity Detection with Limited-Capacity Fronthaul
, 2016 Cloud-Radio Access Network (C-RAN) is characterized by a hierarchical structure in which the baseband processing functionalities of remote radio heads (RRHs) are implemented by means of cloud computing at a Central Unit (CU).
Dimitrova, Tamara +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Method and apparatus for fault tolerance [PDF]
, 1993 A method and apparatus for achieving fault tolerance in a computer system having at least a first central processing unit and a second central processing unit.
Masson, Gerald M., Sullivan, Gregory F.
core +1 more source
Case Studies in Thermal Engineering, 2022 CPUs are widely used in many industries. These components require electrical energy for processing and generating heat due to their electrical resistance.
Hexi Wu +3 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source