Results 71 to 80 of about 66,310 (255)

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Public Administration and Political System in France: The Central Role of the State, Administration and Law

open access: yes, 2015
U radu je prikazan francuski upravno-politički sustav, koji po tradicionalnom poimanju počiva na središnjoj ulozi države koja se oslanja na jak upravni aparat kojim dominiraju pravne vrijednosti.
Iva Lopižić, Lopižić, Iva
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

THE ROLE OF THE PUBLIC SECTOR IN CORPORATE SOCIALRESPONSIBILITY DEVELOPMENT IN LITHUANIA

open access: yesEkonomika, 2009
In implementing sustainable development policy, corporate social responsibility and other voluntary business initiatives plays the crucial role. Business plays the central role in economy and its voluntary initiatives such as signing the Global Compact ...
Dalia Štreimikienė, Rasa Pušinaitė
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

The Institutionalization of Ethics and the Role of Human Resources in Ethical Behavior in the Public Sector [PDF]

open access: yesOvidius University Annals: Economic Sciences Series
In order to identify the ethical peculiarities of human resources management in the public administration, we studied the specialized literature, as well as documents published by international and European bodies.
Adela-Maria Militaru (Popa)   +2 more
doaj  

Applying the Skip Navigation Links in the Context of the Websites’ Accessibility of Central Public Administration Bodies in the Nitra Region

open access: yesSocietas et Iurisprudentia, 2014
The study focuses in its main aim on seeking yet undetected or undefined deficits in relation to applying the skip navigation mechanism on the websites of the central public administration bodies in the Nitra Region in the context of improving the websites accessibility and it consists of two separate parts. The first part presents a basic introduction
openaire   +7 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

Organizational Peculiarities of Local Self-government Bodies

open access: yesНаукові записки НаУКМА: Юридичні науки, 2019
The article is focused on organizational peculiarities of local self-government bodies in different countries. The article also provides analysis of constitutions of different countries and normative-legal acts that define the status of local self ...
Oleksandra Mohylna
doaj   +1 more source

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