Results 241 to 250 of about 603,565 (306)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Unbiased recording and identification of thymic cellular interactomes using synthetic Notch receptors. [PDF]

Nat Commun
Sánchez-Lanzas R, Jiménez-Pompa A, Smith E, Sumaria N, Barclay J, Kalampalika F, Pennington DJ, Efremova M, Ganuza M.   +8 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Point-of-care ultrasound for central venous catheter confirmation and complications in the emergency department: A systematic review and meta-analysis. [PDF]

J Int Med Res
Zhu X, Yang G, Jin Y, Ye Y, Lin J, Tang M, Chen L, Chen W, Wang X.   +8 more
europepmc   +1 more source

Dynamic Modeling of Solar Central Receivers

, 1981
openaire   +2 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Low-angle subduction of the Indian plate and megathrust geometry below the Eastern Himalayas. [PDF]

Natl Sci Rev
Bai L, Li H, Chen Z, Zhan H, Li G, Mori J, Ding L.   +6 more
europepmc   +1 more source

Eosinophil-derived neurotoxin as a biomarker to predict the development of asthma after respiratory infection in infant. [PDF]

Transl Pediatr
Huang Y, Li G, Zhang P, Zhang L, Fan Y.
europepmc   +1 more source

Optimized T-shaped resonator via local enhancement model integration within a cell for enhanced Rydberg-atom receiver sensing. [PDF]

Commun Eng
Wu B, Sun Z, Sang D, Liu Y, An Q, Lin Y, Fu Y.   +6 more
europepmc   +1 more source

MRI-Based Classification Systems Combined with Serum CA125 for Predicting Symptom Recurrence After Ultrasound-Guided High-Intensity Focused Ultrasound Ablation Surgery for Adenomyosis: A Retrospective Cohort Study. [PDF]

Int J Womens Health
Tang Y, Tian HD, Chen XM, Wang H, Shen LM, Ni SQ, Su B, Jiang ZJ, Zhu LJ, Luo YX, Shi Q.   +10 more
europepmc   +1 more source