Results 61 to 70 of about 345,428 (274)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Machine Learning-Assisted Ensemble Analysis for the Prediction of Acute Pancreatitis with Acute Kidney Injury

International Journal of General Medicine, 2022
Yi Yang,1 Wei Xiao,2 Xingtai Liu,1 Yan Zhang,1 Xin Jin,1 Xiao Li1 1Department of Clinical Laboratory, The Third Clinical Medical College of the Three Gorges University, Gezhouba Central Hospital of Sinopharm, Yichang, People’s Republic of China ...
Yang Y, Xiao W, Liu X, Zhang Y, Jin X, Li X   +5 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Performance and Techno-Economic Comparison Between Solid-Particle and Molten Salt Concentrated Solar Power Systems

SolarPACES Conference Proceedings
This work presents a comprehensive comparative analysis of second-generation (Gen2) and third-generation (Gen3) concentrated solar power (CSP) technologies.
Ignacio Javier Arias Olivares, Felipe G. Battisti, José Cardemil, Armando Castillejo-Cuberos, Rodrigo Escobar   +4 more
doaj   +1 more source

Performance analysis of modified asymmetrically-clipped optical orthogonal frequency-division multiplexing systems [PDF]

, 2016
A modification to the Asymmetrically-Clipped Optical Orthogonal Frequency-Division Multiplexing (ACO-OFDM) technique is proposed through unipolar encoding.
Andonovic, Ivan, Hussein, Moustafa, Mohamed, Salma, Shalaby, Hossam   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Financial textual sentiment connectedness: Evidence from alternative data

International Journal of Information Management Data Insights
This study investigates the connectedness of various firm-level investor sentiment proxies—news, social media, ESG positive (ESGpos), and ESG negative (ESGneg) sentiment using aggregate connectedness measures and a sample of DJIA stocks between 2015 and ...
Yudhvir Seetharam, Kingstone Nyakurukwa
doaj   +1 more source

On the Efficient Broadcasting of Heterogeneous Services over Band-Limited Channels: Unequal Power Allocation for Wavelet Packet Division Multiplexing

International Journal of Digital Multimedia Broadcasting, 2008
Multiple transmission of heterogeneous services is a central aspect of broadcasting technology. Often, in this framework, the design of efficient communication systems is complicated by stringent bandwidth constraint.
Maurizio Murroni
doaj   +1 more source

Solar thermal power systems point-focusing thermal and electric applications projects. Volume 1: Executive summary [PDF]

The activities of the Point-Focusing Thermal and Electric Applications (PETEA) project for the fiscal year 1979 are summarized. The main thrust of the PFTEA Project, the small community solar thermal power experiment, was completed.
Marriott, A.
core   +1 more source

GDNF‐RET signaling drives pulmonary neuroendocrine cell hyperplasia and allergic airway inflammation

FEBS Letters, EarlyView.
A neuroimmune interaction centered on the PNEC‐ILC2 axis in an asthma model. PNEC‐derived CGRP activates nearby ILC2s, which then release cytokines, including IL‐5 and IL‐13. These cytokines promote eosinophil and macrophage infiltration. Subsequently, GDNF produced by these cells induces PNEC hyperplasia via the GDNF receptors, RET and GFRα1 ...
Tasuku Kawano, Erina Ike, Suguru Okada, Tomoko Takahashi   +3 more
wiley   +1 more source