Results 71 to 80 of about 62,239 (284)

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Diagnostic Criteria for Macular Edema Associated with Venous Occlusions

Acta Biomedica Scientifica, 2020
Background. Macular edema is considered as a risk factor for a significant decrease in the visual acuity and quality of life of the patient, regardless of its cause.
A. G. Shchuko, V. V. Bukina, A. V. Borisova, T. N. Iureva   +3 more
doaj   +1 more source

Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]

, 2012
Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli, Attila Aszodi, Claudio A Franco, Eloi Montanez, Emanuel Rognoni, Filipa Neto, Holger Gerhardt, Holger Gerhardt, Markus Rehberg, Roland Wedlich-Söldner, Ulrich Pohl   +10 more
core   +5 more sources

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science, EarlyView.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
wiley   +1 more source

ROLE OF BEVACIZUMAB FOR PREVENTION OF NEOVASCULAR GLAUCOMA IN ACUTE RETINAL VEIN OCCLUSION [PDF]

Journal of University Medical & Dental College, 2018
: There is a possibility of developing neovascular glaucoma in ischemic type of retinal vein occlusion. Purpose of the study is to determine the role of anti VEGF agent bevacizumab for prevention of neovascular glaucoma in ischemic type of retinal vein ...
Bassam Mubarik , Adeen Akram
doaj   +1 more source

Incidence rates of retinal vascular occlusive diseases from 2011 to 2020 in South Korea: a nationwide cohort study

BMC Ophthalmology
Background Retinal vascular occlusions, including retinal vein occlusion and retinal artery occlusion, are common causes of visual impairment. In order to evaluate the national medical burden and help improve ophthalmic health care policy planning, we ...
Shin Hyeong Park, Bum Jun Kim, Ji Hye Kim, Seung Chan Kim, Rock Bum Kim, Yong Seop Han   +5 more
doaj   +1 more source

Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusion [PDF]

, 2008
Purpose: To evaluate the effect of intravitreal bevacizumab (Avastin) injections on visual acuity (VA) and foveal retinal thickness in patients with macular oedema secondary to branch retinal vein occlusion.Methods: A prospective, non-comparative ...
Alge, C. S., Burger, J., Haritoglou, Christos, Kampik, Anselm, Kook, Daniel, Kreutzer, Thomas C., Kunze, C., Priglinger, Siegfried, Strauss, R., Wolf, A. H.   +9 more
core   +1 more source

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

Concurrent central retinal artery occlusion and branch retinal vein occlusion in giant cell arteritis

Clinical Ophthalmology, 2010
Edward R Chu, Celia S ChenDepartment of Ophthalmology, Flinders Medical Centre and Flinders University, Bedford Park, SA, AustraliaAbstract: Ophthalmic involvement in giant cell arteritis can manifest in a number of ways. Central retinal artery occlusion
Edward R Chu, Celia S Chen
doaj  

Experimental substantiation of the effectiveness of the “massage” retinal veins for treatment of retinal vein occlusion

Бюллетень сибирской медицины, 2018
Objective: evaluate the effectiveness of treatment of retinal vein occlusion with the use of “massage” of retinal veins on the experimental model of photoinduced retinal venous occlusive disease.Materials and methods.
A. A. Krylova, O. I. Krivosheina, O. I. Urazova   +2 more
doaj   +1 more source