Results 131 to 140 of about 49,783 (286)

Safety and efficacy of the therapy with CD4 + CD25highCD127‐T regulatory cells: When paediatric patient becomes adult

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1392-1402, February 2026.
Abstract Aim CD4 + CD25highCD127‐T regulatory cells (Tregs) remain a drug candidate for immunotherapy of type 1 diabetes. We completed three trials testing Tregs in recently diagnosed type 1 diabetes children. Here, we looked for long‐term safety and efficacy aspects important in the authorisation of this therapy.
Marta Bandura, Magdalena Piotrowska‐Mieczkowska, Matylda Hennig, Mateusz Gliwiński, Anna Wołoszyn‐Durkiewicz, Julia Schoenhoff, Milena Dybowska, Anna Alska, Piotr Gutknecht, Bartosz Trzeciak, Katarzyna Stefańska, Paulina Glasner, Marcin Hellmann, Jacek Burzyński, Arkadiusz Michalak, Janusz Siebert, Dorota Iwaszkiewicz‐Grześ, Małgorzata Myśliwiec, Piotr Trzonkowski   +18 more
wiley   +1 more source

Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications

Advanced Materials, Volume 38, Issue 2, 8 January 2026.
Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi, Chunyao Wang, Xuan Mei, Ben Zhang, Junxi Wu, Rylie A. Green, Yu Shrike Zhang, Wenmiao Shu   +7 more
wiley   +1 more source

Vascular Occlusions following Ocular Surgical Procedures: A Clinical Observation of Vascular Complications after Ocular Surgery

Journal of Ophthalmology, 2017
Background. Ocular vascular occlusions following intraocular procedures are a rare complication. We report a case series of patients with retinal vascular occlusions or anterior ischemic optic neuropathy (AION) after anterior and posterior segment ...
Charlotte Fischer, Anne Bruggemann, Annette Hager, Josep Callizo Planas, Johann Roider, Hans Hoerauf   +5 more
doaj   +1 more source

Central retinal vein occlusion associated with creatine supplementation and dehydration

, 2021
Omar Moussa, Royce W. S. Chen
openalex   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, Volume 13, Issue 5, 27 January 2026.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Experimental substantiation of the effectiveness of the “massage” retinal veins for treatment of retinal vein occlusion

Бюллетень сибирской медицины, 2018
Objective: evaluate the effectiveness of treatment of retinal vein occlusion with the use of “massage” of retinal veins on the experimental model of photoinduced retinal venous occlusive disease.Materials and methods.
A. A. Krylova, O. I. Krivosheina, O. I. Urazova   +2 more
doaj   +1 more source

Central Retinal Vein Occlusion in a Patient with Retinal Vasculitis and Crohn’s Disease [PDF]

, 2014
Lígia Figueiredo, Renata Rothwell, Arnaldo Brandão, Sofia Fonseca   +3 more
openalex   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Cortical Microvascular Pulsatility in the Aging Mouse Brain and the Confounding Effects of Anesthesia

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Multi‐modal optical imaging reveals microvascular pulsatility in the brain cortex of awake and anaesthetized mice. Awake hemodynamics in male mice are found to be remarkably stable until late life, with flow pulsatility being significantly higher than in females, despite similar average perfusion.
Mia Viuf Skøtt, Elizaveta Melnikova, Eugenio Gutiérrez, Vladimir Matchkov, Leif Østergaard, Dmitry D Postnov   +5 more
wiley   +1 more source

Synergistic Combination of Additive One‐ and Two‐Photon Polymerization Printing Methods to Fabricate 3D Microstructured Perfusable Angiogenesis–on–a–Chip Systems

Engineering in Life Sciences, Volume 26, Issue 1, January 2026.
ABSTRACT Tissue engineering, and in particular the development of organ‐on‐a‐chip (OOC) models, holds significant promise for advancing personalized medicine and reducing the use of animal models. The integration of microfluidics and advanced biomaterials in OOC systems provides controlled microenvironments and fosters the creation of physiologically ...
Daria Sokoliuk, Rizlene Bouhaya, Peter Haeger, Kathrin Godthardt, Daniel Fetting, Lenard Spiecker, Heinrich Spiecker, Alexander Rockenbach, Holger Rothe, Klaus Liefeith, Doris Heinrich   +10 more
wiley   +1 more source